血红蛋白萨基α2β2 14 亮氨酸-脯氨酸（a11）结构与功能

Haemoglobin Saki alpha 2 beta 2 14 Leu-Pro(a11) structure and function.

作者信息

Beuzard Y, Basset P, Braconnier F, el Gammal H, Martin L, Oudard J L, Thillet J, Caburi J

出版信息

Biochim Biophys Acta. 1975 May 30;393(1):182-7. doi: 10.1016/0005-2795(75)90229-9.

Abstract

The characterization of haemoglobin Saki alpha 2 beta 2 14 Leu-Pro(a11) is described. This new mutation is unique since it only induces modification of the stability of the molecule. In vitro precipitation of haemoglobin Saki upon heat or in the presence of chemicals is compared to the stability of haemoglobin A and haemoglobin S.

摘要

描述了血红蛋白萨基α2β2 14 亮氨酸-脯氨酸（a11）的特征。这种新突变是独特的，因为它仅诱导分子稳定性的改变。将血红蛋白萨基在加热或存在化学物质时的体外沉淀与血红蛋白A和血红蛋白S的稳定性进行了比较。