Nasim Muhammad Jawad, Asad Muhammad Hassham Hassan Bin, Sajjad Ashif, Khan Shujaat Ali, Mumtaz Amara, Farzana Kalsoom, Rashid Zarmina, Murtaza Ghulam
Department of Pharmacy, COMSATS Institute of Information and Technology, Abbottabad 22060, Pakistan.
Acta Pol Pharm. 2013 May-Jun;70(3):387-94.
Although the majority of serious cases in the world are concerned with snake bite envenomation, but those which are caused by scorpion stings are also famous for causing extreme pain. The present view is an attempt to enlist scientifically ignored medicinal plants of Pakistan exhibiting anti-scorpion venom activity. In this review data of 35 medicinal plants is collected with their families, parts used, distribution in Pakistan, and major constituents present in plant. Amaranthaceae, Astraceae and Euphorbiaceae represent 3 species. Anacardiaceae, Asclepidaceae and Liliaceae represent 2 species. Araceae, Capparidaceae, Ceasalpinaceae, Cyperaceae, Labiatae, Lamiaceae, Meliaceae, Menispermaceae, Oleaceae, Oxalidaceae, Pinaceae, Polygonaceae, Rhamnaceae, Rubiaceae, Solanaceae, Valerianaceae and Zingiberaceae represented single medicinal plant with anti scorpion potential. According to literature, all parts are used in anti scorpion envenomination. Leaves exhibit 30%, whole plant 9%, fruit, bark and seeds 8% anti scorpion activity. Bulb and stems show 5% contribution in this respect and twigs, resins, inflorescence, latex and flowers express 3% potential. This article may assist the researchers to bring innovation in natural product field for scorpion bite envenomation. However, these medicinal plants are still requiring pharmacological and phytochemical investigation in order to be claimed as effective in scorpion bite envenomation.
虽然世界上大多数严重病例与蛇咬伤中毒有关，但蝎子蜇伤引起的病例也因会导致剧痛而闻名。本文旨在罗列巴基斯坦一些具有抗蝎毒活性但在科学上被忽视的药用植物。在这篇综述中，收集了35种药用植物的数据，包括它们所属的科、使用的部位、在巴基斯坦的分布以及植物中所含的主要成分。苋科、菊科和大戟科各有3种植物。漆树科、萝摩科和百合科各有2种植物。天南星科、十字花科、苏木科、莎草科、唇形科、唇形科、楝科、防己科、木犀科、酢浆草科、松科、蓼科、鼠李科、茜草科、茄科、缬草科和姜科各有1种具有抗蝎毒潜力的药用植物。根据文献记载，所有部位都可用于抗蝎毒。叶子的抗蝎毒活性为30%，全株为9%，果实、树皮和种子为8%。鳞茎和茎在这方面的贡献为5%，嫩枝、树脂、花序、乳胶和花的潜力为3%。本文或许能帮助研究人员在天然产物领域针对蝎子蜇伤中毒带来创新。然而，这些药用植物仍需进行药理和植物化学研究，才能被认定对蝎子蜇伤中毒有效。
