Prasai A, Nix P A, Aye M, Atkin S, England R J
Department of Otolaryngology and Head and Neck Surgery, Hull Royal Infirmary, UK.
J Laryngol Otol. 2013 Jul;127(7):681-4. doi: 10.1017/S0022215113001254. Epub 2013 Jun 13.
The role of total thyroidectomy in the management of patients with Graves' disease remains controversial. However, there is increasing evidence to support the role of the procedure as a safe and definitive treatment for Graves' disease.
Patients were identified from a prospective thyroid database of the multidisciplinary thyroid clinic at Hull Royal Infirmary. All case notes were independently reviewed to confirm the data held on the database.
Over a 7-year period, the senior author has performed 206 total thyroidectomies for Graves' disease. The incidence of temporary recurrent laryngeal nerve palsy and hypoparathyroidism was 3.4 per cent and 24 per cent respectively. There was one case of permanent unilateral recurrent laryngeal nerve palsy, and 3.9 per cent of patients developed permanent hypoparathyroidism. There has been no relapse of thyrotoxicosis.
In the context of a multidisciplinary thyroid clinic, total thyroidectomy should be offered as a safe and effective first-line treatment option for Graves' disease.
甲状腺全切除术在格雷夫斯病患者治疗中的作用仍存在争议。然而，越来越多的证据支持该手术作为格雷夫斯病安全且确定性治疗方法的作用。
从赫尔皇家医院多学科甲状腺诊所的前瞻性甲状腺数据库中识别患者。所有病历均经过独立审查以确认数据库中的数据。
在7年期间，资深作者为格雷夫斯病实施了206例甲状腺全切除术。暂时性喉返神经麻痹和甲状旁腺功能减退的发生率分别为3.4%和24%。有1例永久性单侧喉返神经麻痹，3.9%的患者发生永久性甲状旁腺功能减退。甲状腺毒症无复发。
在多学科甲状腺诊所的背景下，甲状腺全切除术应作为格雷夫斯病安全有效的一线治疗选择。
