Dermatology and Genetic Medicine, Division of Molecular Medicine, Medical Sciences Institute (Level 4), University of Dundee, Dundee DD1 5EH, UK.
J Invest Dermatol. 2013 Jul;133(7):1709-11. doi: 10.1038/jid.2013.14.
ABCC11 genotype affects apocrine secretory cell function and determines individual body odor phenotype. Rodriguez et al. have applied genetic epidemiology using predetermined phenotype data to demonstrate an association between a single-nucleotide polymorphism (rs17822931) and the human behavior of deodorant application. Individuals with the ABCC11 genotype predicting a nonodorous phenotype report a significantly lower frequency of deodorant use.
ABCC11 基因型影响顶泌汗腺细胞的功能，并决定个体体臭表型。罗德里格斯等人应用遗传流行病学，使用预先确定的表型数据，证明了单核苷酸多态性（rs17822931）与人类使用除臭剂的行为之间存在关联。预测无臭表型的 ABCC11 基因型个体报告使用除臭剂的频率明显较低。
