Departments of 1Gynaecology and Obstetrics and 2Pathology, Faculty of Medicine, Minia University, El-Minia, Egypt.
J Low Genit Tract Dis. 2014 Jan;18(1):21-5. doi: 10.1097/LGT.0b013e31828ce581.
To evaluate the accuracy of visual inspection with acetic acid (VIA) in determining the site, the size, and the number of cervical biopsies in patients with positive cervical cytology.
This study included 486 patients with positive cervical cytology who presented to the Gynaecological Oncology Unit of Minia Maternity University Hospital, Egypt, in the period between January 2008 and September 2011. Visual inspection with acetic acid was done for all patients. They were classified into 2 groups according to the results of VIA. Group 1 included VIA-negative women, whereas group 2 included VIA-positive women. All patients were reexamined with colposcopy to prove or disprove the presence of lesions. Cervical biopsies were taken from patients with positive VIA or colposcopically confirmed lesions using punch biopsy forceps. Biopsies were sent for histologic examination.
In group 1, 100 patients were VIA-negative, 66 of them were histopathologically free, whereas 34 patients had positive biopsy results. Group 2 included 386 patients: 31 were histologically free, 239 had cervical intraepithelial neoplasia (CIN) 1, whereas 116 had CIN 2 or worse.
Visual inspection with acetic acid is a good test for aiding the diagnosis of CIN and may be helpful in determining the site, the size, and the number of biopsies in patients with positive cytologic results. Instead of colposcopy, VIA can be used in developing countries where colposcopic services are not available.
评估醋酸视觉检查（VIA）在确定细胞学阳性患者宫颈活检的部位、大小和数量方面的准确性。
本研究纳入了 2008 年 1 月至 2011 年 9 月期间在埃及米尼亚妇产大学医院妇科肿瘤病房就诊的 486 例细胞学阳性患者。对所有患者均行醋酸 VIA 检查。根据 VIA 结果将患者分为 2 组，VIA 阴性组（第 1 组）包括 VIA 阴性的患者，VIA 阳性组（第 2 组）包括 VIA 阳性的患者。所有患者均经阴道镜复查以证实或排除病变的存在。对 VIA 阳性或阴道镜检查确认有病变的患者采用活检钳行宫颈活检。将活检组织送病理检查。
第 1 组 100 例患者 VIA 阴性，其中 66 例组织学正常，34 例活检阳性。第 2 组包括 386 例患者：31 例组织学正常，239 例为宫颈上皮内瘤变（CIN）1 级，116 例为 CIN 2 级或更高级别病变。
醋酸 VIA 是一种辅助 CIN 诊断的良好检查方法，有助于确定细胞学阳性患者的活检部位、大小和数量。在缺乏阴道镜检查服务的发展中国家，可以用 VIA 代替阴道镜检查。
