Jin Wangxun, Zhang Chengwu, He Xiaodong, Xu Yuyun, Wang Li, Zhao Zhongsheng
Departments of Hepatology and Biliary Surgery, Zhejiang Cancer Hospital, Hangzhou 310000, P.R China ; Department of Abdominal Tumor Surgery, Zhejiang Cancer Hospital, Hangzhou 310000, P.R China.
Oncol Lett. 2013 May;5(5):1629-1632. doi: 10.3892/ol.2013.1248. Epub 2013 Mar 12.
The aim of this study was to investigate the differences between images of large adenoma of the gallbladder and the protruding type carcinoma of the gallbladder. A retrospective study was performed on 130 patients who underwent cholecystectomy or biopsy for gallbladder polypoid lesions larger than 10 mm; among them, 20 patients were malignant and 110 patients were benign. Patients' details including ultrasonography (US), computed tomography (CT) and magnetic resonance (MR) findings were analyzed. All patients whose lesions were >15 mm by US, had CT or MR scans to further determine the nature of the lesion; two patients who were suspected to have a malignant lesion due to their large tumor size were benign by histological examination. Distinct differences were found between large adenoma and protruding type of gallbladder carcinoma. There were distinct differences between adenomas and the protruding type gallbladder cancers, and there was a pathological basis for the differences. Benign tumors had a more homogeneous texture, had spaces between the tumor and the gallbladder wall and a relatively normal configuration of the gallbladder wall. Based on these findings, certain lesions could be definitively diagnosed as benign adenomas and could help in treatment strategy.
本研究的目的是探讨胆囊大腺瘤与胆囊隆起型癌的图像差异。对130例因胆囊息肉样病变大于10mm而接受胆囊切除术或活检的患者进行了回顾性研究；其中20例为恶性，110例为良性。分析了患者的详细资料，包括超声（US）、计算机断层扫描（CT）和磁共振（MR）检查结果。所有超声显示病变>15mm的患者均进行了CT或MR扫描，以进一步确定病变性质；两名因肿瘤较大而怀疑为恶性病变的患者经组织学检查为良性。胆囊大腺瘤与胆囊隆起型癌之间存在明显差异。腺瘤与胆囊隆起型癌之间存在明显差异，且这些差异有病理基础。良性肿瘤质地更均匀，肿瘤与胆囊壁之间有间隙，胆囊壁结构相对正常。基于这些发现，某些病变可明确诊断为良性腺瘤，并有助于制定治疗策略。
