基于氨酯键特定切割的比率型近红外荧光探针的研制
Development of ratiometric near-infrared fluorescent probes using analyte-specific cleavage of carbamate.
机构信息
Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, PR China.
出版信息
Org Biomol Chem. 2013 Jul 28;11(28):4577-80. doi: 10.1039/c3ob40932e. Epub 2013 Jun 12.
PMID:23760313
Abstract
We report a facile method to design NIR ratiometric fluorescent probes in terms of analyte-induced carbamate cleavage. Two examples, CyNB and CyNN3, exhibit a significant analyte-triggered response with ratiometric fluorescence change in the NIR range and dual-emission ratiometry in living cells.
摘要
我们报道了一种简便的方法，即根据分析物诱导的氨基甲酸酯裂解来设计近红外比率荧光探针。两个实例 CyNB 和 CyNN3 在近红外范围内表现出显著的分析物触发响应，具有比率荧光变化和活细胞中的双发射比率测量。
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