Department of Chemistry, University of North Bengal, Darjeeling, 734013, India.
Amino Acids. 2013 Oct;45(4):755-77. doi: 10.1007/s00726-013-1519-8. Epub 2013 Jun 13.
Qualitative and quantitative analysis of molecular interaction prevailing in glycine, L-alanine, L-valine and aqueous solution of β-cyclodextrin (β-CD) have been probed by thermophysical properties. Density (ρ), viscosity (η), and ultrasonic speed (u) measurements have been reported at different temperatures. The extent of interaction (solute-solvent interaction) is expressed in terms of the limiting apparent molar volume ([Formula: see text]), viscosity B-coefficient and limiting apparent molar adiabatic compressibility ([Formula: see text]). The changes on the enthalpy ([Formula: see text]) and entropy ([Formula: see text]) of the encapsulation analysis give information about the driving forces governing the inclusion. The temperature dependence behaviour of partial molar quantities and group contributions to partial molar volumes has been determined for the amino acids. The trends in transfer volumes, [Formula: see text], have been interpreted in terms of solute-cosolute interactions based on a cosphere overlap model. The role of the solvent (aqueous solution of β-CD) and the contribution of solute-solute and solute-solvent interactions to the solution complexes have also been analyzed through the derived properties.
通过热物理性质研究了甘氨酸、L-丙氨酸、L-缬氨酸和β-环糊精（β-CD）水溶液中分子相互作用的定性和定量分析。在不同温度下报告了密度（ρ）、粘度（η）和超声速度（u）的测量值。相互作用的程度（溶质-溶剂相互作用）用极限表观摩尔体积（[Formula: see text]）、粘度 B 系数和极限表观摩尔绝热压缩系数（[Formula: see text]）表示。包合分析中焓（[Formula: see text]）和熵（[Formula: see text]）的变化提供了关于控制包合的驱动力的信息。对于氨基酸，确定了偏摩尔量和偏摩尔体积的基团贡献随温度的变化行为。根据共球重叠模型，根据转移体积 [Formula: see text] 的趋势，解释了溶质-共溶质相互作用。还通过推导的性质分析了溶剂（β-CD 的水溶液）的作用以及溶质-溶质和溶质-溶剂相互作用对溶液配合物的贡献。
