Physico-Chemical Studies of Some Bio-active Solutes in Pure Methanoic Acid.

The apparent molar volume (ΦV), viscosity B-coefficient, adiabatic compressibility (ΦK) and molar refraction (R) of L-Glycine, L-Alanine, L-Valine and L-Leucine have been determined in methanoic acid at 298.15 K from density (ρ), viscosity (η), speed of sound (u) and refractive index (nD) respectively. The apparent molar volumes have been extrapolated to zero concentration to obtain the limiting values at infinite dilution using Masson equation. The limiting apparent molar volume (ΦV0) and experimental slopes (S*V) obtained from the Masson equation have been interpreted in terms of solute-solvent and solute-solute interactions, respectively. The viscosity data were analyzed using the Jones-Dole equation, and the derived parameters A and B have also been interpreted in terms of solute-solute and solute-solvent interactions, respectively in the solutions. Molar refraction (R) have been calculated using the Lorentz-Lorenz equation. Limiting apparent molar adiabatic compressibilities (ΦK0) of these amino acids at infinite dilution were evaluated.