General Unit of Psychology, Adult Neuropsychology Outpatients' Department, Belcolle Hospital, AUSL Viterbo, Viterbo, Italy.
Aging Clin Exp Res. 2013 Aug;25(4):403-9. doi: 10.1007/s40520-013-0062-5. Epub 2013 Jun 13.
The aim of this study was to evaluate the efficacy of a cognitive rehabilitation intervention performed in an Alzheimer's Day Care Center for 12 months on patients suffering from Alzheimer's-type dementia with moderate cognitive impairment. In the cognitive rehabilitation treatment of moderate cognitive impairment, the leading cognitive stimulation techniques are reality orientation therapy and cognitive training. While these techniques are meant to treat different cognitive environments, there is scarce documentation in literature about their joint use. For this purpose, the therapy was administered to two groups of patients: the experimental group was composed of four subjects and received cognitive rehabilitation (cognitive training plus reality orientation therapy); the control group was composed of five subjects and received aspecific stimulation. To assess subjects' responses the Milan Overall Dementia Assessment and the Mini-Mental State Examination were used for the cognitive domain, while the Geriatric Depression Scale was used for the affective sphere. The results indicated that the subjects submitted to cognitive rehabilitation obtain statistically significant results compared to the control group from the 9 months of treatment, in clinical terms; they maintain their cognitive performance, while no significant differences were found between the two groups as far as the affective domain is concerned.
本研究旨在评估在阿尔茨海默病日托中心进行为期 12 个月的认知康复干预对患有中度认知障碍的阿尔茨海默病型痴呆患者的疗效。在中度认知障碍的认知康复治疗中，主要的认知刺激技术是现实定向疗法和认知训练。虽然这些技术旨在治疗不同的认知环境，但文献中关于它们联合使用的资料很少。为此，将该疗法应用于两组患者：实验组由 4 名患者组成，接受认知康复（认知训练加现实定向疗法）；对照组由 5 名患者组成，接受特定刺激。为了评估受试者的反应，使用米兰整体痴呆评估和迷你精神状态检查来评估认知领域，而使用老年抑郁量表来评估情感领域。结果表明，与对照组相比，接受认知康复的受试者在治疗 9 个月后在临床方面获得了统计学上显著的结果；他们保持了认知表现，而在情感领域，两组之间没有发现显著差异。
