van der Mei H C, Perdok J F, Genet M, Rouxhet P G, Busscher H J
Clin Prev Dent. 1990 Apr-May;12(1):25-9.
To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined. The surface-free energies were estimated from contact angle measurements; whereas the elemental compositions were determined by X-ray photoelectron spectroscopy. Surface-free energies of ground and polished enamel (88 +/- 8 mJ.m-2 and saliva-coated enamel (103 +/- 4) became similar (109-112) upon adsorption of CPC. Also, the N/C concentration ratios of the ground and polished enamel surface (0.06) and saliva-coated enamel (0.21) become equal upon CPC adsorption. The N/C concentration ratio after CPC adsorption (N/C = 0.04) corresponds with the value expected on basis of the molecular structure of CPC. The strongest evidence for adsorption of CPC to both ground and polished enamel and saliva-coated enamel is presented by the double nitrogen N1s peak. This double nitrogen1s peak is not observed for ground and polished enamel nor for enamel with a salivary coating on top of adsorbed CPC, which indicates that adsorbed CPC can be completely screened by salivary proteins. This study demonstrates that CPC has a definite capacity to adsorb both on ground and polished enamel as well as on pellicle-coated enamel.
为了确定氯化十六烷基吡啶（CPC）吸附对有无唾液成分吸附的人牙釉质润湿性和表面元素组成的影响，测定了表面自由能和元素组成。表面自由能通过接触角测量估算；而元素组成则通过X射线光电子能谱测定。在吸附CPC后，研磨和抛光牙釉质的表面自由能（88±8 mJ·m-2）和唾液包被牙釉质的表面自由能（103±4）变得相似（109 - 112）。此外，研磨和抛光牙釉质表面（0.06）以及唾液包被牙釉质表面（0.21）的N/C浓度比在吸附CPC后变得相等。CPC吸附后的N/C浓度比（N/C = 0.04）与基于CPC分子结构预期的值相对应。CPC吸附到研磨和抛光牙釉质以及唾液包被牙釉质上的最有力证据是双氮N1s峰。在研磨和抛光牙釉质以及在吸附的CPC之上有唾液涂层的牙釉质中未观察到这个双氮1s峰，这表明吸附的CPC可以被唾液蛋白完全屏蔽。本研究表明，CPC具有在研磨和抛光牙釉质以及薄膜包被牙釉质上吸附的确定能力。
