Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
J Clin Microbiol. 2013 Aug;51(8):2766-8. doi: 10.1128/JCM.00982-13. Epub 2013 Jun 12.
Real-time PCR (qPCR) was positive in 72/150 (48%) blood samples of newborns with congenital toxoplasmosis. Among infants with active retinochoroiditis, 68% had positive qPCR results, while positivity was 29% (P=0.009) in the absence of ocular involvement. Positive qPCR was associated with the presence of retinochoroidal lesions, with an odds ratio of 2.8.
实时聚合酶链反应(qPCR)在 150 例先天性弓形虫病新生儿的 72/150(48%)血液样本中呈阳性。在有活动性脉络膜视网膜炎的婴儿中,68%的 qPCR 结果为阳性,而在没有眼部受累的情况下,阳性率为 29%(P=0.009)。qPCR 阳性与视网膜脉络膜病变的存在相关,优势比为 2.8。