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上颌骨同时出现牙根囊肿和黏液表皮样癌:一场诊断噩梦。

Simultaneous radicular cyst and mucoepidermoid carcinoma in the maxilla: a diagnostic nightmare.

作者信息

Nabil Syed, Lo Regina Cheuk Lam, Choi Wing Shan

机构信息

Faculty of Dentistry, The National University of Malaysia, Kuala Lumpur, Malaysia.

出版信息

BMJ Case Rep. 2013 Jun 12;2013:bcr2013010290. doi: 10.1136/bcr-2013-010290.

DOI:10.1136/bcr-2013-010290
PMID:23761616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3703046/
Abstract

We present a case of a 20-year-old woman presenting initially with an asymptomatic palatal swelling. Radiographic examination showed a cyst at the right maxilla with bucco-lingual expansion and perforation of palatal bone. Incisional biopsy was carried out via a buccal approach and the result revealed a benign odontogenic cyst, in keeping with radicular cyst. The patient was then scheduled for cyst enucleation. During the procedure, it was found that the palatal lesion was unrelated to the maxillary cyst. Incisional biopsy of the palatal mass was carried out and revealed a low-grade mucoepidermoid carcinoma. The patient then had a partial maxillectomy with fibula flap reconstruction. There was no recurrence at postoperative 1 year follow-up and she was rehabilitated with dental implants.

摘要

我们报告一例20岁女性患者,最初表现为无症状的腭部肿胀。影像学检查显示右侧上颌骨有一个囊肿,伴有颊舌向扩展及腭骨穿孔。通过颊侧入路进行了切开活检,结果显示为良性牙源性囊肿,符合根尖囊肿。随后该患者被安排进行囊肿摘除术。在手术过程中,发现腭部病变与上颌囊肿无关。对腭部肿物进行了切开活检,结果显示为低级别黏液表皮样癌。该患者随后接受了部分上颌骨切除术及腓骨瓣重建术。术后1年随访未见复发,她接受了牙种植修复。

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本文引用的文献

1
Glandular odontogenic cyst: systematic review.腺牙源性囊肿:系统评价。
Dentomaxillofac Radiol. 2010 Mar;39(3):127-39. doi: 10.1259/dmfr/30943934.
2
Synchronous papillary carcinoma in thyroglossal duct cyst and thyroid gland: case report and review of literature.甲状舌管囊肿与甲状腺同步发生乳头状癌:病例报告及文献复习
Head Neck. 2009 Oct;31(10):1387-91. doi: 10.1002/hed.21029.
3
Glandular odontogenic cyst: a challenge in diagnosis and treatment.腺源性牙源性囊肿:诊断与治疗中的挑战
Oral Dis. 2008 Oct;14(7):575-81. doi: 10.1111/j.1601-0825.2007.01428.x. Epub 2008 Jan 31.
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Aetiopathology of maxillary swelling--a 3-year prospective study.上颌肿胀的病因病理学——一项为期3年的前瞻性研究。
Eur Arch Otorhinolaryngol. 2007 Nov;264(11):1295-9. doi: 10.1007/s00405-007-0350-9. Epub 2007 Jul 5.
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Ameloblastic carcinoma ex ameloblastoma: report of a case-possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation.成釉细胞瘤恶变的成釉细胞癌:1例报告——p16基因CpG岛高甲基化可能参与恶性转化
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jan;103(1):72-6. doi: 10.1016/j.tripleo.2006.01.021. Epub 2006 Aug 2.
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Intra-oral minor salivary gland tumors: a clinicopathological study of 546 cases.口腔内小唾液腺肿瘤:546例临床病理研究
Oral Oncol. 2007 May;43(5):463-70. doi: 10.1016/j.oraloncology.2006.04.008. Epub 2006 Sep 18.
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Squamous cell carcinoma arising in a second branchial cleft cyst.起源于第二鳃裂囊肿的鳞状细胞癌。
Am J Clin Oncol. 2004 Feb;27(1):96-100. doi: 10.1097/01.coc.0000047127.46594.c0.
8
Salivary gland tumours.唾液腺肿瘤
Oral Dis. 2002 Sep;8(5):229-40. doi: 10.1034/j.1601-0825.2002.02870.x.
9
Mucoepidermoid carcinoma of the salivary glands: clinicopathologic review of 108 patients treated at the National Cancer Institute of Milan.涎腺黏液表皮样癌:米兰国立癌症研究所治疗的108例患者的临床病理回顾
Ann Surg Oncol. 2002 Aug;9(7):688-95. doi: 10.1007/BF02574486.
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Synchronous benign and malignant salivary gland tumors in ipsilateral glands: a report of two cases and a review of literature.同侧腺体中同时存在的良性和恶性唾液腺肿瘤:两例报告及文献复习
Head Neck. 2002 Mar;24(3):301-6. doi: 10.1002/hed.10048.