• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

采用颊脂垫瓣修复部分上颌骨切除术后缺损并应用4-己基间苯二酚：1例病例报告

Reconstruction of partial maxillectomy defect with a buccal fat pad flap and application of 4-hexylresorcinol: a case report.

作者信息

Seok Hyun, Kim Min-Keun, Kim Seong-Gon

机构信息

Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea.

出版信息

J Korean Assoc Oral Maxillofac Surg. 2016 Dec;42(6):370-374. doi: 10.5125/jkaoms.2016.42.6.370. Epub 2016 Dec 27.

DOI:10.5125/jkaoms.2016.42.6.370
PMID:28053908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5206243/
Abstract

Mucoepidermoid carcinoma (MEC) is the most common type of malignant neoplasm in the minor salivary gland. The hard palate is a frequently involved site of MEC. The treatment of low-grade MEC on the hard palate is wide local resection with a tumor-free margin. In the present case, the maxillary defect was reconstructed using a buccal fat pad (BFP) flap, followed by application of 4-hexylresorcinol (4HR) ointment for 2 weeks. The grafted BFP successfully covered the tumor resection defect without tension and demonstrated complete re-epithelialization without any complications.

摘要

黏液表皮样癌（MEC）是小唾液腺最常见的恶性肿瘤类型。硬腭是MEC常累及的部位。硬腭低度MEC的治疗方法是进行切缘无瘤的广泛局部切除。在本病例中，采用颊脂垫（BFP）瓣修复上颌骨缺损，随后应用4-己基间苯二酚（4HR）软膏2周。移植的BFP瓣成功无张力地覆盖了肿瘤切除缺损，且显示完全重新上皮化，无任何并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/083f692f718b/jkaoms-42-370-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/bd60aa19769c/jkaoms-42-370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/e3b6e2fc9015/jkaoms-42-370-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/56af8f59f80a/jkaoms-42-370-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/7efc0569a370/jkaoms-42-370-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/0193138b00a0/jkaoms-42-370-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/083f692f718b/jkaoms-42-370-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/bd60aa19769c/jkaoms-42-370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/e3b6e2fc9015/jkaoms-42-370-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/56af8f59f80a/jkaoms-42-370-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/7efc0569a370/jkaoms-42-370-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/0193138b00a0/jkaoms-42-370-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/901c/5206243/083f692f718b/jkaoms-42-370-g006.jpg

相似文献

1
Reconstruction of partial maxillectomy defect with a buccal fat pad flap and application of 4-hexylresorcinol: a case report.采用颊脂垫瓣修复部分上颌骨切除术后缺损并应用4-己基间苯二酚：1例病例报告
J Korean Assoc Oral Maxillofac Surg. 2016 Dec;42(6):370-374. doi: 10.5125/jkaoms.2016.42.6.370. Epub 2016 Dec 27.
2
Buccal Myomucosal Flap Reconstruction After Resection of Palatal Mucoepidermoid Carcinoma.
Ann Plast Surg. 2019 Nov;83(5):538-541. doi: 10.1097/SAP.0000000000001949.
3
Reconstruction of cheek mucosal defect with a buccal fat pad flap in a squamous cell carcinoma patient: a case report and literature review.颊脂垫瓣修复鳞状细胞癌患者颊黏膜缺损：1例报告及文献复习
Maxillofac Plast Reconstr Surg. 2018 May 25;40(1):11. doi: 10.1186/s40902-018-0150-8. eCollection 2018 Dec.
4
Medium-sized buccal mucosa defect reconstruction with buccal advancement flap in mucoepidermoid carcinoma ex pleomorphic adenoma: a case report.多形性腺瘤恶变黏液表皮样癌中使用颊部推进皮瓣修复中型颊黏膜缺损：1例报告
Ann Med Surg (Lond). 2023 Nov 16;86(1):525-529. doi: 10.1097/MS9.0000000000001514. eCollection 2024 Jan.
5
Surgery for Cystadenoma of the Retromolar Pad Area With Reconstruction Using a Buccal Fat Pad Flap: A Case Report.使用颊脂垫瓣修复磨牙后垫区囊腺瘤的手术：一例报告
Cureus. 2022 Jul 26;14(7):e27314. doi: 10.7759/cureus.27314. eCollection 2022 Jul.
6
Mucoepidermoid carcinoma of minor salivary glands: a clinical study of 16 cases and review of the literature.小涎腺黏液表皮样癌：16例临床研究及文献复习
Oral Dis. 2006 Jul;12(4):364-70. doi: 10.1111/j.1601-0825.2005.01166.x.
7
Pedicled buccal fat pad flap for intraoral malignant defects: A series of 29 cases.带蒂颊脂垫瓣修复口腔恶性肿瘤缺损：29例病例系列
Indian J Plast Surg. 2009 Jan-Jun;42(1):36-42. doi: 10.4103/0970-0358.53010.
8
Mucoepidermoid carcinoma of hard palate.硬腭黏液表皮样癌
Indian J Pathol Microbiol. 2018 Jul-Sep;61(3):397-398. doi: 10.4103/IJPM.IJPM_617_17.
9
The use of buccal fat pad free graft in closure of soft-tissue defects and dehiscence in the hard palate.颊脂垫游离移植在硬腭软组织缺损及裂开修复中的应用
Ann Maxillofac Surg. 2016 Jul-Dec;6(2):241-245. doi: 10.4103/2231-0746.200326.
10
Buccal Fat Pad Flap, an Option for Surgical Reconstruction of Orbital Floor Defect: A Case Report.颊脂垫瓣：眶底缺损手术重建的一种选择：病例报告
J West Afr Coll Surg. 2022 Jan-Mar;12(1):95-99. doi: 10.4103/jwas.jwas_89_22. Epub 2022 Aug 23.

引用本文的文献

1
Osteogenic differentiation of 3D-printed porous tantalum with nano-topographic modification for repairing craniofacial bone defects.具有纳米拓扑修饰的3D打印多孔钽用于修复颅面骨缺损的成骨分化
Front Bioeng Biotechnol. 2023 Aug 21;11:1258030. doi: 10.3389/fbioe.2023.1258030. eCollection 2023.
2
Buccal Fat Pad Graft in Maxillofacial Surgery.口腔颌面外科中的颊脂垫移植
Indian J Surg Oncol. 2021 Dec;12(4):802-807. doi: 10.1007/s13193-021-01436-z. Epub 2021 Sep 8.
3
4-Hexylresorcinol: pharmacologic chaperone and its application for wound healing.

本文引用的文献

1
Topical delivery of 4-hexylresorcinol promotes wound healing via tumor necrosis factor-α suppression.4-己基间苯二酚的局部给药通过抑制肿瘤坏死因子-α促进伤口愈合。
Burns. 2016 Nov;42(7):1534-1541. doi: 10.1016/j.burns.2016.04.016. Epub 2016 May 16.
2
Retrospective study on factors affecting the prognosis in oral cancer patients who underwent surgical treatment only.仅接受手术治疗的口腔癌患者预后影响因素的回顾性研究
Maxillofac Plast Reconstr Surg. 2016 Jan 16;38(1):3. doi: 10.1186/s40902-015-0047-8. eCollection 2016 Dec.
3
Evaluation of bone formation and membrane degradation in guided bone regeneration using a 4-hexylresorcinol-incorporated silk fabric membrane.
4-己基间苯二酚：药理学伴侣及其在伤口愈合中的应用。
Maxillofac Plast Reconstr Surg. 2022 Feb 1;44(1):5. doi: 10.1186/s40902-022-00334-w.
4
Titanium mesh and pedicled buccal fat pad for the reconstruction of maxillary defect: case report.钛网联合带蒂颊脂垫修复上颌骨缺损：病例报告
Maxillofac Plast Reconstr Surg. 2021 Mar 17;43(1):10. doi: 10.1186/s40902-021-00295-6.
5
4-hexylresorcinol-induced protein expression changes in human umbilical cord vein endothelial cells as determined by immunoprecipitation high-performance liquid chromatography.免疫沉淀高效液相色谱法测定 4-己基间苯二酚诱导的人脐静脉内皮细胞蛋白质表达变化。
PLoS One. 2020 Dec 15;15(12):e0243975. doi: 10.1371/journal.pone.0243975. eCollection 2020.
6
Reconstruction of cheek mucosal defect with a buccal fat pad flap in a squamous cell carcinoma patient: a case report and literature review.颊脂垫瓣修复鳞状细胞癌患者颊黏膜缺损：1例报告及文献复习
Maxillofac Plast Reconstr Surg. 2018 May 25;40(1):11. doi: 10.1186/s40902-018-0150-8. eCollection 2018 Dec.
7
Recent advances in the reconstruction of cranio-maxillofacial defects using computer-aided design/computer-aided manufacturing.利用计算机辅助设计/计算机辅助制造技术重建颅颌面缺损的最新进展
Maxillofac Plast Reconstr Surg. 2018 Feb 5;40(1):2. doi: 10.1186/s40902-018-0141-9. eCollection 2018 Dec.
8
Maxillary resection for cancer, zygomatic implants insertion, and palatal repair as single-stage procedure: report of three cases.上颌骨癌切除术、颧骨种植体植入及腭部修复一期手术：三例报告
Maxillofac Plast Reconstr Surg. 2017 May 25;39(1):13. doi: 10.1186/s40902-017-0112-6. eCollection 2017 Dec.
使用含4-己基间苯二酚的丝织物膜评估引导骨再生中骨形成和膜降解情况。
Maxillofac Plast Reconstr Surg. 2015 Sep 30;37(1):32. doi: 10.1186/s40902-015-0034-0. eCollection 2015 Dec.
4
Treatment of pathologic fracture following postoperative radiation therapy: clinical study.术后放射治疗后病理性骨折的治疗：临床研究
Maxillofac Plast Reconstr Surg. 2015 Sep 29;37(1):31. doi: 10.1186/s40902-015-0032-2. eCollection 2015 Dec.
5
Facelift incision and superficial musculoaponeurotic system advancement in parotidectomy: case reports.腮腺切除术中的面部提升切口及表浅肌肉腱膜系统推进：病例报告
Maxillofac Plast Reconstr Surg. 2015 Nov 2;37(1):40. doi: 10.1186/s40902-015-0040-2. eCollection 2015 Dec.
6
Mucoepidermoid carcinoma of the base of tongue.舌根黏液表皮样癌
Acta Otorhinolaryngol Ital. 2015 Feb;35(1):58-61.
7
Mucoepidermoid carcinoma of the palate in a 5-year-old girl: case report and literature review.一名5岁女孩腭部黏液表皮样癌：病例报告及文献复习
Oral Maxillofac Surg. 2014 Dec;18(4):465-9. doi: 10.1007/s10006-014-0461-6. Epub 2014 Aug 12.
8
Inhibition of foreign body giant cell formation by 4- hexylresorcinol through suppression of diacylglycerol kinase delta gene expression.通过抑制二酰基甘油激酶 δ 基因表达来抑制异物巨细胞形成的 4-己基间苯二酚。
Biomaterials. 2014 Oct;35(30):8576-84. doi: 10.1016/j.biomaterials.2014.06.050. Epub 2014 Jul 11.
9
Simultaneous radicular cyst and mucoepidermoid carcinoma in the maxilla: a diagnostic nightmare.上颌骨同时出现牙根囊肿和黏液表皮样癌：一场诊断噩梦。
BMJ Case Rep. 2013 Jun 12;2013:bcr2013010290. doi: 10.1136/bcr-2013-010290.
10
4-hexylresorcinol stimulates the differentiation of SCC-9 cells through the suppression of E2F2, E2F3 and Sp3 expression and the promotion of Sp1 expression.4-己基间苯二酚通过抑制 E2F2、E2F3 和 Sp3 的表达以及促进 Sp1 的表达来刺激 SCC-9 细胞的分化。
Oncol Rep. 2012 Aug;28(2):677-81. doi: 10.3892/or.2012.1845. Epub 2012 Jun 1.