Singh Nim J, Kumari Archana, Catanzaro Roberto, Marotta Francesco
Department of Microbiology, C.C.S. University, Meerut-250005, India.
Acta Biomed. 2012 Dec;83(3):197-201.
The prevalence of dual infection was 2.8% (26/927). Majority of these patients had presented with acute flare of a chronic liver disease (42.3%) followed by acute jaundice (38.5%).We found HEV infection to be was highly prevalent among 20 to 40 years of age group. In the case of HBV only 5.37% (5/93) children were affected in the age group 0-10 years.
Serum samples from 1147 proven HEV infection suspected were collected and tested for HBsAg and HEV (IgM) antibodies using enzyme linked immunosorbent assay kits (bio Merieux, France).
There were the 32.16% (367/1141) HEV positive cases. We found maximum HEV positivity in the age group of 21-30 years. There were 2.8% (26/927) HEV and HBV dully infected patients. The total 44.68% (273/611) suspected of acute hepatitis/jaundice were HEV positive.
The HEV found to be was highly prevalent among 20 to 40 years of age group. The males were more frequent than females for HEV and HBV infection. In the children's, there were lower attack of both HEV and HBV. The maximum patients were having acute hepatitis/jaundice in both HEV and HBV infection. There were 26 dually infected patients in 12 months.
双重感染的患病率为2.8%（26/927）。这些患者大多数表现为慢性肝病急性发作（42.3%），其次是急性黄疸（38.5%）。我们发现戊型肝炎病毒（HEV）感染在20至40岁年龄组中高度流行。仅就乙型肝炎病毒（HBV）而言，0至10岁年龄组中仅有5.37%（5/93）的儿童受到感染。
收集1147例经证实疑似戊型肝炎病毒感染患者的血清样本，使用酶联免疫吸附测定试剂盒（法国生物梅里埃公司）检测乙肝表面抗原（HBsAg）和戊型肝炎病毒（IgM）抗体。
戊型肝炎病毒阳性病例占32.16%（367/1141）。我们发现21至30岁年龄组中戊型肝炎病毒阳性率最高。有2.8%（26/927）的患者同时感染了戊型肝炎病毒和乙型肝炎病毒。总共44.68%（273/611）疑似急性肝炎/黄疸的患者戊型肝炎病毒呈阳性。
戊型肝炎病毒感染在20至40岁年龄组中高度流行。戊型肝炎病毒和乙型肝炎病毒感染男性比女性更常见。在儿童中，戊型肝炎病毒和乙型肝炎病毒的感染率较低。戊型肝炎病毒和乙型肝炎病毒感染的患者中，大多数患有急性肝炎/黄疸。12个月内有26例双重感染患者。
