Division of Cancer Prevention and Control, The Ohio State University College of Medicine, 1590 North High St, Suite 525, Columbus, OH 43201, USA.
Am J Public Health. 2013 Aug;103(8):1419-27. doi: 10.2105/AJPH.2012.301189. Epub 2013 Jun 13.
We conducted a longitudinal study to examine human papillomavirus (HPV) vaccine uptake among male adolescents and to identify vaccination predictors.
In fall 2010 and 2011, a national sample of parents with sons aged 11 to 17 years (n = 327) and their sons (n = 228) completed online surveys. We used logistic regression to identify predictors of HPV vaccination that occurred between baseline and follow-up.
Only 2% of sons had received any doses of HPV vaccine at baseline, with an increase to 8% by follow-up. About 55% of parents who had ever received a doctor's recommendation to get their sons HPV vaccine did vaccinate between baseline and follow-up, compared with only 1% of parents without a recommendation. Fathers (odds ratio = 0.29; 95% confidence interval = 0.09, 0.80) and non-Hispanic White parents (odds ratio = 0.29; 95% confidence interval = 0.11, 0.76) were less likely to have vaccinated sons. Willingness to get sons HPV vaccine decreased from baseline to follow-up among parents (P < .001) and sons (P = .003).
Vaccination against HPV remained low in our study and willingness to vaccinate may be decreasing. Physician recommendation and education about HPV vaccine for males may be key strategies for improving vaccination.
我们进行了一项纵向研究，以考察男性青少年接种人乳头瘤病毒（HPV）疫苗的情况，并确定疫苗接种的预测因素。
在 2010 年秋季和 2011 年，一项针对父母及其 11 至 17 岁儿子的全国性抽样调查（n=327 对父母和 228 名儿子）完成了在线调查。我们使用逻辑回归来确定基线和随访期间 HPV 疫苗接种的预测因素。
仅有 2%的儿子在基线时接种过任何剂量的 HPV 疫苗，随访时增加到 8%。约 55%的曾接受过医生推荐为儿子接种 HPV 疫苗的父母在基线和随访期间进行了接种，而未接受过推荐的父母中只有 1%进行了接种。父亲（比值比=0.29；95%置信区间=0.09，0.80）和非西班牙裔白人父母（比值比=0.29；95%置信区间=0.11，0.76）更不可能为儿子接种疫苗。父母（P<0.001）和儿子（P=0.003）的 HPV 疫苗接种意愿从基线到随访期间都有所下降。
在我们的研究中，HPV 疫苗接种率仍然较低，接种意愿可能正在下降。医生推荐和对男性 HPV 疫苗的教育可能是提高疫苗接种率的关键策略。
