Programa de Pós-Graduação em Nutrição, Universidade Federal de São Paulo - UNIFESP, Brazil.
Appetite. 2013 Oct;69:168-73. doi: 10.1016/j.appet.2013.05.018. Epub 2013 Jun 10.
The regulation of energy balance is influenced by physical exercise. Although some studies show a stimulation of hormones related to food intake, others show that exercise provides satiety.
The aim of this study was to compare the effects of aerobic training (AT) and aerobic plus resistance training (AT+RT) on anorexigenic and orexigenic factors in obese adolescents undergoing interdisciplinary weight loss therapy.
A total of 26 obese adolescents, aged 15-19 years with BMI≥P95 were submitted to 12 months of interdisciplinary intervention (clinical support, nutrition, psychology and physical exercise) and divided into two groups, aerobic training (AT) (n=13) or aerobic plus resistance training (AT+RT) (n=13), which were matched according to gender and body mass. Blood samples were collected to analyze orexigenic factors (AgRP, NPY, MCH) and the anorexigenic factor alpha-MSH.
The AT and AT+RT groups significantly reduced body mass, body mass index and body fat mass (kg) during the therapy. The AT group showed no significant changes in body lean mass (kg), whereas the AT+RT group showed an increase in body lean mass (kg) during the interdisciplinary intervention. There was an increase in AgRP levels (ng/ml) only in the AT+RT group after 6 months of interdisciplinary intervention compared with baseline condition. Conversely, α-MSH levels (ng/ml) increased only in the AT group after 12 months of interdisciplinary intervention compared with baseline condition.
Aerobic training (AT) as part of an interdisciplinary therapy is more effective than aerobic plus resistance training (AT+RT) to improve secretion of anorexigenic/orexigenic factors in obese adolescents.
能量平衡的调节受体育锻炼的影响。虽然一些研究表明运动刺激了与食物摄入有关的激素，但其他研究表明运动提供了饱腹感。
本研究旨在比较有氧运动（AT）和有氧加抗阻训练（AT+RT）对接受跨学科减肥治疗的肥胖青少年的摄食和摄食因子的影响。
共有 26 名年龄在 15-19 岁、BMI≥P95 的肥胖青少年接受了 12 个月的跨学科干预（临床支持、营养、心理和体育锻炼），并分为两组，有氧运动（AT）（n=13）或有氧加抗阻训练（AT+RT）（n=13），两组根据性别和体重进行匹配。采集血样分析摄食因子（AgRP、NPY、MCH）和厌食因子α-MSH。
AT 和 AT+RT 组在治疗期间体重、体重指数和体脂量（kg）显著降低。AT 组的去脂体重（kg）无显著变化，而 AT+RT 组在跨学科干预期间去脂体重（kg）增加。与基线相比，仅 AT+RT 组在跨学科干预 6 个月后 AgRP 水平（ng/ml）升高。相反，仅 AT 组在跨学科干预 12 个月后α-MSH 水平（ng/ml）升高。
作为跨学科治疗的一部分，有氧运动（AT）比有氧加抗阻训练（AT+RT）更有效地改善肥胖青少年的摄食和摄食因子的分泌。
