Larocque L, Carignan G, Sved S
Health and Welfare Canada, Drug Residues Section, Bureau of Drug Research, Ottawa, Ontario.
J Assoc Off Anal Chem. 1990 May-Jun;73(3):365-7.
A survey on the presence of sulfamethazine (sulfadimidine) residues in consumer milk has been conducted in 10 cities across Canada. In each city, homogenized milk was purchased at 3 different retail outlets, each supplied by different processing plants. A total of 30 samples was analyzed by a liquid chromatographic method. The limit of quantitation was 5 ppb. In addition to automatic integration, visual inspection of the chromatograms was required to distinguish between low concentrations of sulfamethazine and 2 unknown interfering peaks. Two samples, from different cities, contained 11.4 and 5.24 ppb of the drug. Drug identity was confirmed by mass spectrometry. All other samples appeared to be free of the drug.
在加拿大的10个城市开展了一项关于市售牛奶中磺胺二甲嘧啶残留情况的调查。在每个城市，均从3个不同的零售网点购买了均质牛奶，每个网点的牛奶由不同的加工厂供应。总共30个样本采用液相色谱法进行了分析。定量限为5 ppb。除了自动积分外，还需要对色谱图进行目视检查，以区分低浓度的磺胺二甲嘧啶和2个未知干扰峰。来自不同城市的2个样本含有11.4 ppb和5.24 ppb的该药物。通过质谱法确认了药物的特性。所有其他样本似乎均未含有该药物。
