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本文引用的文献

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Nutrition for healthy term infants: recommendations from birth to six months.足月健康婴儿的营养：从出生到六个月的建议
Can J Diet Pract Res. 2012 Winter;73(4):204. doi: 10.3148/73.4.2012.204.
2
Antidepressant Use During Breastfeeding.母乳喂养期间使用抗抑郁药。
Curr Womens Health Rev. 2011 Feb;7(1):28-34. doi: 10.2174/157340411794474784.
3
Estimation of desvenlafaxine transfer into milk and infant exposure during its use in lactating women with postnatal depression.估计去甲文拉法辛在产后抑郁症哺乳期妇女中的转移及其对婴儿的暴露量。
Arch Womens Ment Health. 2011 Feb;14(1):49-53. doi: 10.1007/s00737-010-0188-9. Epub 2010 Oct 7.
4
Assessment of infant dose through milk in a lactating woman taking amisulpride and desvenlafaxine for treatment-resistant depression.评估服用氨磺必利和去甲文拉法辛治疗难治性抑郁症的哺乳期妇女通过乳汁摄入的婴儿剂量。
Ther Drug Monit. 2010 Dec;32(6):704-7. doi: 10.1097/FTD.0b013e3181f88f70.
5
Canadian Network for Mood and Anxiety Treatments (CANMAT) clinical guidelines for the management of major depressive disorder in adults. III. Pharmacotherapy.加拿大情绪与焦虑治疗网络（CANMAT）成人重度抑郁症管理临床指南。三、药物治疗。
J Affect Disord. 2009 Oct;117 Suppl 1:S26-43. doi: 10.1016/j.jad.2009.06.041. Epub 2009 Aug 11.
6
Maternal depressive symptoms in the postnatal period are associated with long-term impairment of mother-child bonding.产后母亲的抑郁症状与母婴情感联结的长期受损有关。
Arch Womens Ment Health. 2006 Sep;9(5):273-8. doi: 10.1007/s00737-006-0149-5. Epub 2006 Sep 8.
7
Perinatal depression: prevalence, screening accuracy, and screening outcomes.围产期抑郁症：患病率、筛查准确性及筛查结果
Evid Rep Technol Assess (Summ). 2005 Feb(119):1-8. doi: 10.1037/e439372005-001.
8
Pooled analysis of antidepressant levels in lactating mothers, breast milk, and nursing infants.哺乳期母亲、母乳和哺乳婴儿中抗抑郁药水平的汇总分析。
Am J Psychiatry. 2004 Jun;161(6):1066-78. doi: 10.1176/appi.ajp.161.6.1066.
9
The effect of postpartum depression on child cognitive development and behavior: a review and critical analysis of the literature.产后抑郁症对儿童认知发展和行为的影响：文献综述与批判性分析
Arch Womens Ment Health. 2003 Nov;6(4):263-74. doi: 10.1007/s00737-003-0024-6.
10
Drug therapy for breast-feeding women.哺乳期妇女的药物治疗。
N Engl J Med. 2000 Jul 13;343(2):118-26. doi: 10.1056/NEJM200007133430208.

哺乳期抗抑郁药使用的最新进展。

Update on antidepressant use during breastfeeding.

出版信息

Can Fam Physician. 2013 Jun;59(6):633-4.

PMID:23766044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3681447/
Abstract

QUESTION

Many of my patients who are diagnosed with postpartum depression want to continue breastfeeding. How safe are the newer antidepressant medications during breastfeeding?

ANSWER

The newer antidepressants transfer into breast milk in low amounts and have not been associated with serious adverse events. Therefore, the antidepressant most effective for the woman should be considered.

摘要

问题

许多被诊断为产后抑郁症的患者都希望继续母乳喂养。在母乳喂养期间，新型抗抑郁药物的安全性如何？

答案

新型抗抑郁药会以低剂量转移到母乳中，且尚未与严重不良事件相关联。因此，应考虑对该女性最有效的抗抑郁药物。