Drug Ther Bull. 2013 Jun;51(6):69-72. doi: 10.1136/dtb.2013.6.0187.
Around 40-50% of women experience at least one urinary tract infection (UTI) during their lifetime and 20-30% of these have a recurrence within 3-4 months of the initial infection.¹ Recurrent UTI (usually defined as three episodes in the last 12 months or two episodes in the last 6 months) can have a considerable impact on a woman's quality of life. Each episode of acute UTI in young women is typically associated with about 6 days of symptoms, 2.4 days of restricted activities and 0.4 days of bed rest.¹ Antibacterial prophylaxis is effective in preventing recurrent episodes, but at the expense of unwanted effects and a risk of promoting bacterial resistance. Here we assess the efficacy of different antibacterial regimens and non-antibacterial alternatives (cranberry, probiotics, oestrogens, immunostimulation, hyaluronic acid and chondroitin, acupuncture and herbs) in the prevention of recurrent uncomplicated UTIs in women.
约40%-50%的女性在其一生中至少经历过一次尿路感染（UTI），其中20%-30%的患者在初次感染后的3-4个月内会复发。¹复发性尿路感染（通常定义为过去12个月内发作三次或过去6个月内发作两次）会对女性的生活质量产生相当大的影响。年轻女性的每一次急性尿路感染发作通常伴有约6天的症状、2.4天的活动受限和0.4天的卧床休息。¹抗菌预防在预防复发方面有效，但会带来不良影响并存在促进细菌耐药性的风险。在此，我们评估了不同抗菌方案和非抗菌替代方法（蔓越莓、益生菌、雌激素、免疫刺激、透明质酸和软骨素、针灸和草药）在预防女性复发性单纯性尿路感染中的疗效。
