Division Infectious Diseases, Department of Internal Medicine, Academic Medical Center, Room F4-217, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Division Infectious Diseases, Department of Internal Medicine, Academic Medical Center, Room F4-217, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Infect Dis Clin North Am. 2014 Mar;28(1):135-47. doi: 10.1016/j.idc.2013.10.001. Epub 2013 Dec 7.
Recurrent urinary tract infections (UTIs) are common, especially in women. Low-dose daily or postcoital antimicrobial prophylaxis is effective for prevention of recurrent UTIs and women can self-diagnose and self-treat a new UTI with antibiotics. The increasing resistance rates of Escherichia coli to antimicrobial agents has, however, stimulated interest in nonantibiotic methods for the prevention of UTIs. This article reviews the literature on efficacy of different forms of nonantibiotic prophylaxis. Future studies with lactobacilli strains (oral and vaginal) and the oral immunostimulant OM-89 are warranted.
复发性尿路感染（UTI）很常见，尤其是在女性中。小剂量每日或性交后抗菌预防可有效预防复发性 UTI，女性可自行诊断和使用抗生素自我治疗新的 UTI。然而，大肠杆菌对抗菌药物的耐药率不断上升，促使人们对预防 UTI 的非抗生素方法产生了兴趣。本文综述了不同形式的非抗生素预防措施的疗效文献。未来有必要对乳杆菌（口服和阴道）和口服免疫刺激剂 OM-89 进行研究。
