Department of Psychiatry, University of Connecticut Health Center, Farmington, Connecticut 06030, USA.
Yale J Biol Med. 2013 Jun 13;86(2):235-44. Print 2013 Jun.
Depression and comorbid cognitive impairment in the elderly can be difficult to distinguish from dementia. Adding to the complex differential is that depression may be part of a bipolar illness rather than a unipolar mood disorder. A diligent workup and close monitoring of patients can inform appropriate treatment and can make the difference between recovery and persistence of symptoms. The present case will illustrate how a comprehensive workup utilizing extensive data gathering, laboratory workup, use of neuropsychological testing, neuroimaging, and timely treatment can lead to successful clinical outcomes that can be sustained for many years.
老年人的抑郁和并发认知障碍可能难以与痴呆区分。更复杂的是，抑郁可能是双相情感障碍的一部分，而不是单相心境障碍。仔细的检查和对患者的密切监测可以告知适当的治疗方法，并可以在症状的恢复和持续之间产生差异。本病例将说明如何通过综合检查利用广泛的数据收集、实验室检查、神经心理学测试、神经影像学和及时治疗来获得成功的临床结果，并持续多年。
