金催化的烯丙基与磺酰胺的分子间氢胺化反应。
Gold-catalyzed intermolecular hydroamination of allenes with sulfonamides.
机构信息
School of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, PR China.
出版信息
Beilstein J Org Chem. 2013 May 29;9:1045-50. doi: 10.3762/bjoc.9.117. Print 2013.
Abstract
A co-catalyst of (PPh3)AuCl/AgOTf for the intermolecular hydroamination of allenes with sulfonamides is shown. The reaction proceeded smoothly under mild conditions for differently substituted allenes giving N-allylic sulfonamides in good yields with high regioselectivity and E-selectivity.
摘要
（PPh3）AuCl/AgOTf 的共催化剂被用于展示与磺酰胺的烯丙基间的分子内氢胺化反应。该反应在温和条件下顺利进行，对于不同取代的烯丙基，以高区域选择性和 E 选择性得到 N-烯丙基磺酰胺，收率良好。
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