一例与索拉非尼治疗晚期肝细胞癌相关的横纹肌溶解症病例。
A case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma.
作者信息
Tsuji Kunihiro, Takemura Kenichi, Minami Keisuke, Teramoto Ryota, Nakashima Keisuke, Yamada Shinya, Doyama Hisashi, Oiwake Hisanori, Hasatani Kenkou
机构信息
Department of Gastroenterology, Ishikawa Prefectural Central Hospital, 2-1 Kuratsuki-higashi, Kanazawa, Ishikawa 920-8530 Japan ; Department of General Medicine, Suzu General Hospital, Suzu, Japan.
出版信息
Clin J Gastroenterol. 2013 Jun;6(3):255-7. doi: 10.1007/s12328-013-0381-2. Epub 2013 May 17.
We report on a case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. A 70-year-old man was admitted to our hospital with fatigue, myalgia and an elevated creatine phosphokinase level. He was diagnosed as rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. After discontinuation of sorafenib, his fatigue and myalgia resolved and his creatine phosphokinase level returned to normal. Rhabdomyolysis related to sorafenib treatment is rare adverse effect. This is the first detailed case report of rhabdomyolysis related to sorafenib treatment.
我们报告了一例与索拉非尼治疗晚期肝细胞癌相关的横纹肌溶解症病例。一名70岁男性因疲劳、肌痛和肌酸磷酸激酶水平升高入住我院。他被诊断为与索拉非尼治疗晚期肝细胞癌相关的横纹肌溶解症。停用索拉非尼后，他的疲劳和肌痛症状消失，肌酸磷酸激酶水平恢复正常。与索拉非尼治疗相关的横纹肌溶解症是一种罕见的不良反应。这是首例关于索拉非尼治疗相关横纹肌溶解症的详细病例报告。
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