Lau Esther Yuet Ying, Eskes Gail A, Morrison Debra L, Rajda Malgorzata, Spurr Kathleen F
Sleep Laboratory, Department of Psychology, 6/F Jockey Club Tower, The University of Hong Kong, Pokfulam Road, Hong Kong.
Sleep Disord. 2013;2013:140725. doi: 10.1155/2013/140725. Epub 2013 Mar 31.
We investigated the role of daytime sleepiness and sleep quality in psychosocial outcomes of patients with obstructive sleep apnea (OSA) treated with continuous positive airway pressure (CPAP). Thirty-seven individuals with moderate to severe OSA and compliant with CPAP treatment for at least 3 months were compared to 27 age- and education-matched healthy controls. The OSA group and the control group were studied with overnight polysomnography (PSG) and compared on measures of daytime sleepiness (Epworth Sleepiness Scale), sleep quality (Pittsburg Sleep Quality Index), mood (Beck Depression Inventory, Profile of Mood States), and functional outcomes (Functional Outcomes of Sleep Questionnaire). After CPAP treatment, the OSA group improved on sleep quality and sleepiness. As a group, they did not differ from controls on sleep architecture after CPAP. The OSA group also showed significant improvements in functional outcomes and was comparable to controls on mood and functional outcomes. Persistent difficulties included lowered activity level and residual sleepiness in some individuals. Sleepiness was found to be a significant predictor of mood and affective states, while both sleepiness and sleep quality predicted functional outcomes. These results highlight the importance of assessment and intervention targeting psychosocial functioning and sleepiness in individuals with OSA after treatment.
我们研究了日间嗜睡和睡眠质量在接受持续气道正压通气(CPAP)治疗的阻塞性睡眠呼吸暂停(OSA)患者心理社会结局中的作用。将37例中度至重度OSA且CPAP治疗依从至少3个月的个体与27例年龄和教育程度匹配的健康对照者进行比较。对OSA组和对照组进行整夜多导睡眠图(PSG)检查,并比较日间嗜睡(爱泼沃斯嗜睡量表)、睡眠质量(匹兹堡睡眠质量指数)、情绪(贝克抑郁量表、情绪状态剖面图)和功能结局(睡眠问卷功能结局)指标。CPAP治疗后,OSA组的睡眠质量和嗜睡情况有所改善。作为一个整体,CPAP治疗后他们在睡眠结构方面与对照组没有差异。OSA组在功能结局方面也有显著改善,在情绪和功能结局方面与对照组相当。持续存在的困难包括一些个体的活动水平降低和残留嗜睡。发现嗜睡是情绪和情感状态的重要预测因素,而嗜睡和睡眠质量均预测功能结局。这些结果凸显了治疗后对OSA个体心理社会功能和嗜睡进行评估及干预的重要性。