Stelmach-Mardas Marta, Mardas Marcin, Iqbal Khalid, Tower Robert J, Boeing Heiner, Piorunek Tomasz
Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthurt-Scheunert Alee Str. 114-116, 14558, Nuthetal, Germany.
Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str 27/33, 60-572, Poznan, Poland.
Health Qual Life Outcomes. 2016 Jul 27;14(1):111. doi: 10.1186/s12955-016-0516-5.
The aim of this study was to analyze the association between depression, quality of life and dietary intake in newly diagnosed Obstructive Sleep Apnea (OSA) patients.
From 153 eligible patients suffering from sleep disturbances, 64 met inclusion and exclusion criteria. The polysomnography was used for OSA diagnosis. The quality of life (QOL) was assessed by WHOQOL-BREF questionnaire, self-reported chronotype by morningness-eveningness questionnaire and level of depression by Beck's Depression Inventory. Blood pressure and parameters of glucose and lipid metabolism were assessed by routine methods. The dietary intake was evaluated by 24-hr dietary recalls.
Significantly negative associations were found between depression inventory and QOL. Better QOL for physical health and social relationships was observed in the "definitely morning" chronotype. The "morning type" of patients was positively related to the intake of fat, monounsaturated fatty acids and vitamin B12. Correlations between QOL and diastolic blood pressure, HDL-cholesterol, TG, fasting glucose, as well as protein and vitamin B6 intake were found.
In conclusion, both chornotype and depression influence QOL in OSA patients where morning type is associated with better physical health and social relationships and increase in depression index deteriorate physical health, psychological and social relationship QOL domains. QOL as well as depression and chornotype are also influenced by selected cardio-metabolic factors and dietary intake.
本研究旨在分析新诊断的阻塞性睡眠呼吸暂停(OSA)患者的抑郁、生活质量与饮食摄入之间的关联。
从153名有睡眠障碍的合格患者中,64名符合纳入和排除标准。采用多导睡眠图进行OSA诊断。生活质量(QOL)通过WHOQOL-BREF问卷进行评估,通过晨型-夜型问卷自我报告昼夜节律类型,通过贝克抑郁量表评估抑郁水平。通过常规方法评估血压以及糖脂代谢参数。通过24小时饮食回顾评估饮食摄入情况。
抑郁量表与生活质量之间存在显著的负相关。在“绝对晨型”昼夜节律类型中观察到更好的身体健康和社会关系生活质量。患者的“晨型”与脂肪、单不饱和脂肪酸和维生素B12的摄入量呈正相关。发现生活质量与舒张压、高密度脂蛋白胆固醇、甘油三酯、空腹血糖以及蛋白质和维生素B6摄入量之间存在相关性。
总之,昼夜节律类型和抑郁均影响OSA患者的生活质量,其中晨型与更好的身体健康和社会关系相关,抑郁指数升高会使身体健康、心理和社会关系生活质量领域恶化。生活质量以及抑郁和昼夜节律类型还受到某些心脏代谢因素和饮食摄入的影响。