lialikov S A, Bedin P G, Ermak S Iu, Ianovich R V
Eksp Klin Farmakol. 2013;76(3):31-4.
To estimate the ability of cycloferon to influence a microbiological landscape of tonsils surface in often ill children (OIC), the microflora of tonsils before and after a standard course of this preparation in a group of 68 preschool children classified into OIC category. It is established that the microbe landscape of tonsils surface after a course of cycloferon therapy is characterized by reduction of microflora variety, decrease in bacteria titer (including S. aureus), and reduction ion then number of strains resistant to benzylpenicillin, clindamycin, and vancomycin. Thus, it is possible to recommend cycloferon for rehabilitation of OIC.
为评估环孢素对经常生病儿童（OIC）扁桃体表面微生物群落的影响能力，对68名被归类为OIC的学龄前儿童在使用该制剂标准疗程前后的扁桃体微生物群进行了研究。结果表明，环孢素治疗疗程后扁桃体表面的微生物群落特征为微生物种类减少、细菌滴度降低（包括金黄色葡萄球菌），以及对苄青霉素、克林霉素和万古霉素耐药的菌株数量减少。因此，推荐使用环孢素用于OIC的康复治疗。
