Gerow G, Callton M, Meyer J J, Demchak J J, Christiansen J
Research Department, Northwestern College of Chiropractic, Lombard, IL.
J Manipulative Physiol Ther. 1990 Jun;13(5):257-61.
Although numerous clinical thermographic studies are available, few basic science studies using thermography have been performed. As such, evidence suggesting the diagnostic use of thermography is often mired in the complexity of human ailments. This study thermographically evaluated the hind paws of rats. Rats acted as their own controls using the contralateral side as reference. Rats were separated into two groups: sham operated rats and rats with complete sciatic nerve transection. Rats that received sciatic transection were noted to have a 5.1 degrees C rise of the affected plantar hind paw immediately following transection. There was a statistical difference in right vs. left up to 42 days, and a return to symmetry at 63 days. The sham operated group did not experience a rise in temperature of the affected hind paw. Controlled animal studies of this type may be an aid in understanding clinical thermography.
尽管有大量的临床热成像研究,但使用热成像的基础科学研究却很少。因此,表明热成像诊断用途的证据往往深陷于人类疾病的复杂性之中。本研究对大鼠的后爪进行了热成像评估。大鼠以对侧作为对照,自身作为对照对象。大鼠被分为两组:假手术组大鼠和坐骨神经完全横断的大鼠。接受坐骨神经横断的大鼠在横断后立即出现受影响的足底后爪温度升高5.1摄氏度。在42天内,左右两侧存在统计学差异,在63天时恢复对称。假手术组受影响的后爪温度没有升高。这种类型的对照动物研究可能有助于理解临床热成像。