Vítovec J, Slíva J
Interni kardio-angiologicka klinika Lekarske fakulty MU a FN u sv Anny Brno.
Vnitr Lek. 2013 May;59(5):397-401.
The article gives an overview of the risk factors for hypertension and the appropriate indication for using a fixed combination of telmisartan and hydrochlorothiazide. It cites large, multicentre clinical trials that demonstrate the efficacy and safety of telmisartan in patients with hypertension and also a metaanalysis of treatment with either telmisartan alone (TELMI) or in combination with hydrochlorothiazide (HCTZ) which shows that it is a very well tolerated and safe treatment for patients across a wide age range.
本文概述了高血压的危险因素以及使用替米沙坦和氢氯噻嗪固定复方制剂的适当指征。文中引用了大型多中心临床试验,这些试验证明了替米沙坦在高血压患者中的疗效和安全性,还引用了一项关于单独使用替米沙坦(TELMI)或与氢氯噻嗪(HCTZ)联合使用的治疗的荟萃分析,该分析表明,对于广泛年龄范围内的患者,这是一种耐受性良好且安全的治疗方法。