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医生对老年期抑郁症的识别:恶劣心境和认知障碍的作用。

Physicians' detection of late-life depression: the roles of dysphoria and cognitive impairment.

机构信息

a Department of Psychology, West Virginia University , Morgantown , West Virginia, USA.

出版信息

Aging Ment Health. 2013;17(8):1030-6. doi: 10.1080/13607863.2013.805403. Epub 2013 Jun 14.

Abstract

OBJECTIVE

To examine factors that impede or facilitate physicians' detection of depression in later life, including cognitive impairment and patients' endorsement of dysphoria.

METHODS

A population-based sample of 344 adults from the Swedish Adoption/Twin Study of Aging (SATSA) was utilized. Physician detection of depression was determined by (1) outpatient medical records, (2) antidepressant prescription, and/or (3) inpatient hospitalization. Depressive symptoms were measured by highest score on the Center for Epidemiologic Studies - Depression Scale (CES-D), administered on six occasions between 1986 and 1994. Endorsement of dysphoria was examined using two items on the CES-D. The Mini-Mental State Examination (MMSE) was used to indicate cognitive impairment.

RESULTS

One-hundred thirty-six individuals were above the cut-off on the CES-D on at least one occasion; however, only 14 of these individuals (10%) were detected as depressed by a physician. Higher CES-D total score was significantly related to physician detection. Furthermore, physicians were most likely to detect depression if the individual endorsed the single CES-D item regarding feeling depressed. A significant interaction was found, such that overall CES-D score was only associated with physician detection among those with higher endorsement of the depressed item. The association between total CES-D and physician detection was not affected by presence of cognitive impairment.

CONCLUSIONS

Depression in later life often goes undetected by physicians. Factors associated with detection include the frequency/severity of symptoms and patients' endorsement specifically of feeling depressed. Results suggest that physicians should routinely assess for other symptoms associated with late-life depression besides dysphoria (e.g., appetite loss, crying spells).

摘要

目的

研究阻碍或促进医生在晚年发现抑郁症的因素,包括认知障碍和患者对抑郁情绪的认可。

方法

利用瑞典收养/双胞胎衰老研究(SATSA)中的 344 名成年人的基于人群的样本。通过(1)门诊病历、(2)抗抑郁药处方和/或(3)住院治疗来确定医生对抑郁症的检测。使用 1986 年至 1994 年期间进行的六次测试中的最高得分,通过流行病学研究中心抑郁量表(CES-D)来衡量抑郁症状。使用 CES-D 上的两个项目来检查抑郁情绪的认可。使用迷你精神状态检查(MMSE)来表示认知障碍。

结果

136 个人在至少一次测试中 CES-D 得分超过了临界值;然而,只有 14 名患者(10%)被医生诊断为抑郁症。较高的 CES-D 总分与医生的诊断显著相关。此外,如果个人认可了关于感到沮丧的单个 CES-D 项目,医生更有可能发现抑郁症。发现存在显著的交互作用,即只有在更高的抑郁项目认可的情况下,总体 CES-D 评分才与医生的诊断相关。认知障碍的存在并不影响 CES-D 总分与医生检测之间的关联。

结论

晚年的抑郁症经常未被医生发现。与检测相关的因素包括症状的频率/严重程度以及患者对抑郁情绪的具体认可。结果表明,医生应常规评估除抑郁情绪以外的与晚年抑郁症相关的其他症状(例如,食欲减退、哭泣发作)。

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本文引用的文献

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Age differences in symptom expression in patients with major depression.年龄差异对重性抑郁症患者症状表现的影响。
Int J Geriatr Psychiatry. 2012 Jun;27(6):601-11. doi: 10.1002/gps.2759. Epub 2011 Jul 19.
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Clinical diagnosis of depression in primary care: a meta-analysis.基层医疗中抑郁症的临床诊断:一项荟萃分析。
Lancet. 2009 Aug 22;374(9690):609-19. doi: 10.1016/S0140-6736(09)60879-5. Epub 2009 Jul 27.
8
Depression in older adults.老年人的抑郁症。
Annu Rev Clin Psychol. 2009;5:363-89. doi: 10.1146/annurev.clinpsy.032408.153621.

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