Department of Surgery, University of California-Davis, Sacramento, CA, United States.
Burns. 2013 Sep;39(6):1048-53. doi: 10.1016/j.burns.2013.05.001. Epub 2013 Jun 13.
The purpose of our study is to validate the Pediatric Risk of Mortality (PRISM) score and compare the accuracy of PRISM predicted outcomes to the Abbreviated Burn Severity Index (ABSI). We hypothesized that the PRISM score is more accurate in predicting mortality and hospital length of stay than the ABSI in children with severe burns.
All children <18 years of age admitted to a regional pediatric burn center between January 1, 2008 and July 1, 2010 were reviewed. Those with a Total Body Surface Area (TBSA) burn ≥20% who were admitted within 7 days of injury were selected for our study. Measured parameters included: demographics, burn characteristics, PRISM and ABSI scores at admission, and outcomes (mortality, hospital length of stay (LOS), ventilator days and cause of death).
A total of 83 patients met criteria and had complete data sets. The mean age (±SEM) was 8.0±0.6 years, mean % TBSA burn 49.9±2.1%, 62.7% were male, and 45.8% had inhalation injury. Hospital LOS was 74.4±7.9 days, with 31.5±4.9 ventilator days. Mean PRISM score ranged from 14.2 to 16.0, with ABSI scores 7.9 to 8.5. Actual overall mortality was 18.1% compared to a PRISM predicted mortality of 19.8±2.5% (p<0.001, r=0.570). ABSI predicted mortality varied from 10 to 20% for a score of 7.9 to 30-50% for a score of 8.5. Logistic regression showed that both PRISM (p<0.001) and ABSI (p<0.001) mortality predictions accurately estimated actual mortality, which remained true in a combined model. ABSI was predictive of hospital LOS (p<0.001) and ventilator days (p<0.001) while PRISM was not (p=0.326 and p=0.863).
Both PRISM and ABSI scores are predictive of mortality in severely burned children. Only ABSI correlates with hospital length of stay and ventilator days, and thus may also be more useful in predicting ICU resource utilization.
本研究旨在验证儿科死亡率风险评分(PRISM),并比较 PRISM 预测结果与简化烧伤严重度指数(ABSI)的准确性。我们假设 PRISM 评分在预测死亡率和住院时间方面比 ABSI 更准确,适用于严重烧伤的儿童。
回顾 2008 年 1 月 1 日至 2010 年 7 月 1 日期间在一家区域性儿科烧伤中心就诊的所有<18 岁的儿童。选择 TBSA 烧伤面积≥20%,且伤后 7 天内入院的患儿进行研究。测量参数包括:人口统计学特征、烧伤特征、入院时的 PRISM 和 ABSI 评分,以及结局(死亡率、住院时间、呼吸机使用天数和死亡原因)。
共有 83 例患儿符合标准并完成了完整的数据集。平均年龄(±SEM)为 8.0±0.6 岁,平均 TBSA 烧伤面积 49.9±2.1%,62.7%为男性,45.8%有吸入性损伤。住院时间为 74.4±7.9 天,呼吸机使用天数为 31.5±4.9 天。PRISM 评分范围为 14.2 至 16.0,ABSI 评分为 7.9 至 8.5。实际总死亡率为 18.1%,而 PRISM 预测死亡率为 19.8±2.5%(p<0.001,r=0.570)。ABSI 预测死亡率在 7.9 分时为 10-20%,在 8.5 分时为 30-50%。逻辑回归显示,PRISM(p<0.001)和 ABSI(p<0.001)死亡率预测均能准确估计实际死亡率,且在联合模型中也成立。ABSI 可预测住院时间(p<0.001)和呼吸机使用天数(p<0.001),而 PRISM 则不能(p=0.326 和 p=0.863)。
PRISM 和 ABSI 评分均能预测严重烧伤儿童的死亡率。只有 ABSI 与住院时间和呼吸机使用天数相关,因此在预测 ICU 资源利用方面可能更有用。