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血浆置换机中红细胞量的损失:用生理盐水冲洗一次性管路并回输的影响。

Loss of red cell mass in a plasmapheresis machine: effect of rinsing the disposable tubing with normal saline and reinfusion.

作者信息

Fischer Thorsten, Surikova Irina, Heesen Ewa, Wilms Galina, Laitinen Teija, Taborski Uwe

机构信息

Deutsche Gesellschaft f. Humanplasma mbH, Plasmazentrum Krefeld, Petersstrasse 122/Behnisch-Haus, D-47798 Krefeld, Germany.

出版信息

Transfus Apher Sci. 2013 Aug;49(1):80-3. doi: 10.1016/j.transci.2013.05.031. Epub 2013 Jun 12.

DOI:10.1016/j.transci.2013.05.031
PMID:23769170
Abstract

The aim of this study was to determine the loss of red cell mass during a plasma donation. If the donor undergoes plasmapheresis 45 times within one year without rinsing the tubing system and reinfusing this normal saline into the donor at the end of the donation, the result is a loss of red cell mass of 11.01 ml per donation. This result translates into an accumulated loss of red cell mass of up to 495.63 ml per year. The loss of blood induced by plasma donations can be reduced to 58.01 ml per year, if the disposable tubing is rinsed with normal saline and reinfused into the donor at the end of each plasma donation.

摘要

本研究的目的是确定血浆捐献过程中红细胞量的损失。如果捐献者在一年内进行45次血浆置换,且不冲洗管路系统,也不在捐献结束时将生理盐水回输给捐献者,那么每次捐献的红细胞量损失为11.01毫升。这一结果意味着每年红细胞量累计损失高达495.63毫升。如果在每次血浆捐献结束时用生理盐水冲洗一次性管路并回输给捐献者,那么血浆捐献引起的血量损失可降至每年58.01毫升。

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