Hanze University of Applied Sciences, Professorship in Health Care and Nursing, Groningen, The Netherlands.
Parkinsonism Relat Disord. 2013 Oct;19(10):878-82. doi: 10.1016/j.parkreldis.2013.05.014. Epub 2013 Jun 12.
Although physical activity is beneficial for Parkinson's disease (PD) patients, many do not meet the recommended levels. The range of physical activity among sedentary PD patients is unknown, as are factors that determine this variability. Hence, we aimed to (1) assess daily physical activity in self-identified sedentary PD patients; (2) compare this with criteria of a daily physical activity guideline; and (3) identify determinants of daily physical activity.
Daily physical activity of 586 self-identified sedentary PD patients was measured with a tri-axial accelerometer for seven consecutive days. Physical fitness and demographic, disease-specific, and psychological characteristics were assessed. Daily physical activity was compared with the 30-min activity guideline. A linear mixed-effects model was estimated to identify determinants of daily physical activity.
Accelerometer data of 467 patients who fulfilled all criteria revealed that >98% of their day was spent on sedentary to light-intensity activities. Eighty-two percent of the participants were 'physically inactive' (0 days/week of 30-min activity); 17% were 'semi-active' (1-4 days/week of 30-min activity). Age, gender, physical fitness, and scores on the Unified Parkinson's Disease Rating Scale explained 69% of the variability in daily physical activity.
Performance-based measurements confirmed that most self-identified sedentary PD patients are 'physically inactive'. However, the variance in daily physical activity across subjects was considerable. Higher age, being female, and lower physical capacity were the most important determinants of reduced daily physical activity. Future therapeutic interventions should aim to improve daily physical activity in these high-risk patients, focusing specifically on modifiable risk factors.
尽管身体活动有益于帕金森病（PD）患者，但许多患者并未达到推荐水平。久坐 PD 患者的身体活动范围尚不清楚，决定这种变异性的因素也不清楚。因此，我们旨在：（1）评估自我认定的久坐 PD 患者的日常身体活动；（2）将其与日常身体活动指南标准进行比较；（3）确定日常身体活动的决定因素。
使用三轴加速度计连续 7 天测量 586 名自我认定的久坐 PD 患者的日常身体活动。评估身体状况和人口统计学、疾病特异性和心理特征。将日常身体活动与 30 分钟活动指南进行比较。采用线性混合效应模型确定日常身体活动的决定因素。
满足所有标准的 467 名患者的加速度计数据显示，他们一天中超过 98%的时间都在进行久坐或低强度活动。82%的参与者是“身体不活跃”（每周 0 天进行 30 分钟的活动）；17%的参与者是“半活跃”（每周 1-4 天进行 30 分钟的活动）。年龄、性别、身体状况和统一帕金森病评定量表评分解释了日常身体活动变异性的 69%。
基于表现的测量证实，大多数自我认定的久坐 PD 患者都是“身体不活跃”的。然而，受试者之间的日常身体活动差异相当大。较高的年龄、女性和较低的身体能力是日常身体活动减少的最重要决定因素。未来的治疗干预措施应旨在提高这些高风险患者的日常身体活动水平，特别关注可改变的危险因素。
