Ahern Leanne, Timmons Suzanne, Lamb Sarah E, McCullagh Ruth
Discipline of Physiotherapy, School of Clinical Therapies, University College Cork, Cork, Ireland.
Centre for Gerontology and Rehabilitation, School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland.
J Frailty Sarcopenia Falls. 2025 Sep 1;10(3):128-149. doi: 10.22540/JFSF-10-128. eCollection 2025 Sep.
Exercise reduces fall risk, sarcopenia and frailty in Parkinson's disease, but motor and non-motor symptoms hinder adherence. This study aimed to feasibility test an exercise intervention with behaviour change techniques, examining recruitment, procedures, and measure responsiveness.
A mixed-methods parallel-arm, single-blinded, randomized feasibility study. Participants (Hoehn and Yahr 1-3) were randomly allocated to intervention or control groups. Both received 12-weeks of education, supervised exercise, and home exercises. The intervention group received additional behaviour change techniques. Enrolment, attendance, adherence, and adverse events were recorded. Outcomes included walking activity, balance, falls, strength, and exercise self-efficacy. Surveys and interviews explored acceptability.
Twenty-six people were screened; sixteen randomized, fourteen completed. Exercise class attendance in both groups was high. Adherence to home exercises was higher in the intervention group (70% vs 63%). No serious adverse events. Time resources were acceptable. Walking activity and aerobic endurance reached minimally important differences. Interviews indicated participants enjoyed the group dynamic and gained skills. Feedback will improve acceptability.
The intervention is feasible and well-accepted. While not designed to measure frailty, sarcopenia, or fall risk directly, enhancing adherence through behaviour change techniques and tailoring interventions to individual preferences maybe a promising strategy to support long-term exercise engagement. ClinicalTrials.gov: ID: NCT06192628.
运动可降低帕金森病患者的跌倒风险、肌肉减少症和衰弱程度,但运动和非运动症状会妨碍患者坚持运动。本研究旨在对一项采用行为改变技术的运动干预进行可行性测试,考察招募情况、程序及测量反应性。
一项混合方法的平行组、单盲随机可行性研究。参与者(霍恩和亚尔分级1 - 3级)被随机分配至干预组或对照组。两组均接受为期12周的教育、监督下的运动及家庭锻炼。干预组还接受额外的行为改变技术。记录入组情况、出勤情况、依从性及不良事件。结果包括步行活动、平衡能力、跌倒情况、力量及运动自我效能感。通过调查和访谈探究可接受性。
筛查了26人;16人随机分组,14人完成研究。两组的运动课程出勤率都很高。干预组的家庭锻炼依从性更高(70%对63%)。无严重不良事件。时间资源可接受。步行活动和有氧耐力达到了最小重要差异。访谈表明参与者喜欢团队氛围并学到了技能。反馈将提高可接受性。
该干预可行且接受度良好。虽然本研究并非旨在直接测量衰弱、肌肉减少症或跌倒风险,但通过行为改变技术提高依从性并根据个人偏好调整干预措施可能是支持长期运动参与的一种有前景的策略。ClinicalTrials.gov标识符:NCT06192628 。