心境障碍青少年和年轻成人的睡眠-觉醒周期和褪黑素节律：单相和双相表型的比较。
Sleep-wake cycle and melatonin rhythms in adolescents and young adults with mood disorders: comparison of unipolar and bipolar phenotypes.
机构信息
Clinical Research Unit, Brain & Mind Research Institute, University of Sydney, 100, Mallett St, 2050 Camperdown, NSW, Australia.
出版信息
Eur Psychiatry. 2013 Sep;28(7):412-6. doi: 10.1016/j.eurpsy.2013.04.001. Epub 2013 Jun 13.
PMID:23769680
Abstract
This study evaluated the potential of circadian measures as early markers of mood disorders subtypes. Patients with bipolar disorders had significantly lower levels and later onset of melatonin secretion than those with unipolar depression. Furthermore, abnormal phase angles between sleep, melatonin and temperature were found in several patients.
摘要
本研究评估了作为情绪障碍亚型早期标志物的昼夜节律测量的潜力。双相情感障碍患者的褪黑素分泌水平明显较低，且分泌时间较晚。此外，在几位患者中发现了睡眠、褪黑素和体温之间的异常相位角。
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