Department of Radiodiagnosis, Lady Hardinge Medical College and Associated Hospitals, New Delhi 110001, India.
Department of Radiodiagnosis, Employees' State Insurance Corporation (ESIC) Model Hospital, Gurgaon 122001, Haryana, India.
Eur J Radiol. 2014 Jan;83(1):47-56. doi: 10.1016/j.ejrad.2013.04.044. Epub 2013 Jun 14.
Pulmonary Langerhans cell histiocytosis (PLCH) is a well known entity in adults but is exceedingly rare in children. It is better described in adults than in children. We describe the current understanding of PLCH in children and a spectrum of radiological findings of PLCH in the paediatric population. On high resolution computed tomography (HRCT), PLCH may have variable appearance depending on the stage of disease, ranging from small interstitial nodular opacities to multiple thin/thick walled cysts (often bizarre in shape), eventually leading to marked parenchymal fibrosis and honeycomb pattern. CT finding of PLCH is similar in adult and paediatric populations with the exception that lung base near the costophrenic angle is spared in adults but almost always involved in children.
肺朗格汉斯细胞组织细胞增生症（PLCH）在成人中是一种众所周知的疾病，但在儿童中极为罕见。它在成人中的描述优于在儿童中的描述。我们描述了儿童中 PLCH 的现有认识，以及儿科人群中 PLCH 的一系列放射学表现。在高分辨率计算机断层扫描（HRCT）上，PLCH 的表现可能因疾病阶段而异，从小的间质结节状混浊到多个薄壁/厚壁囊肿（形状通常很奇特），最终导致明显的实质纤维化和蜂巢样改变。PLCH 的 CT 表现与成人和儿童人群相似，除了成人的肋膈角附近的肺底不受累，但几乎总是累及儿童。
