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儿童间质性肺疾病：分类和影像学表现的最新认识。

Childhood interstitial lung diseases: current understanding of the classification and imaging findings.

机构信息

Department of Radiology, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo, 160-0016, Japan.

Department of Radiology, Musashino-Yowakai Hospital, Tokyo, Japan.

出版信息

Jpn J Radiol. 2024 Sep;42(9):937-952. doi: 10.1007/s11604-024-01603-6. Epub 2024 Jul 16.

DOI:10.1007/s11604-024-01603-6
PMID:39012450
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11364587/
Abstract

Childhood interstitial lung diseases (chILDs) encompass a diverse group of disorders with a high mortality rate and severe respiratory morbidities. Recent investigations have revealed that the classification of adult ILDs is not valid for chILDs, particularly for ILDs of early onset. Therefore, Children's Interstitial Lung Disease Research Cooperative of North America proposed a new classification of chILDs for affected children under 2 years of age, and later another classification for affected individuals between 2 and 18 years of age. In this review, we provide an overview of the imaging findings of chILDs by classification. Most infantile ILDs have unique clinical, radiological, and molecular findings, while the manifestation of pediatric ILDs overlaps with that of adult ILDs.

摘要

儿童间质性肺疾病（chILDs）涵盖了一组具有高死亡率和严重呼吸系统并发症的不同疾病。最近的研究表明，成人间质性肺疾病的分类不适用于 chILDs，特别是对于早发性间质性肺疾病。因此，北美儿童间质性肺疾病研究合作组织提出了一种新的 chILD 分类方法，适用于 2 岁以下的受影响儿童，后来又提出了一种适用于 2 至 18 岁受影响个体的分类方法。在这篇综述中，我们按分类介绍了 chILDs 的影像学表现。大多数婴儿期间质性肺疾病具有独特的临床、放射学和分子表现，而儿科间质性肺疾病的表现与成人间质性肺疾病重叠。

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