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胸交感神经切除术治疗原发性多汗症的长期疗效

Long-term results of thoracic sympathectomy for primary hyperhidrosis.

作者信息

Stefaniak Tomasz J, Ćwigoń Marta

出版信息

Pol Przegl Chir. 2013 May;85(5):247-52. doi: 10.2478/pjs-2013-0038.

DOI:10.2478/pjs-2013-0038
PMID:23770524
Abstract

UNLABELLED

The side effects following thoracic sympathectomy for primary hyperhidrosis include pain and compensatory/ reflex sweating. The aim of the study was the evaluation of the results of the endoscopic sympathicotomy with clips with emphasis on the frequency of side effects following the operation.

MATERIAL AND METHODS

Two-hundred-eighty-three patients were qualified to thoracic T3-T4 sympathicotomy with clips. In all cases bilateral procedure in prone position with CO2 insufflation was performed. The subjective intensity of disease was evaluated by VAS scale (0--no sweating; 10--maximal possible sweating) while the recurrence of the sweating in primary localization, intensity and dynamics of compensatory and plantar sweating were evaluated post-operatively. Follow-up data were obtained during office visits 3, 12 and 36 months after surgery. The overall follow-up response was 74.6%.

RESULTS

There was no mortality. Perioperative morbidity included 6 cases of pneumothorax. The mean duration of surgery was 57 minutes bilaterally. The postoperative intercostal pain was present in all patients (100%) with mean duration of 21.88 days but in 72.6% of cases it did not demand any medication as early as 48 hours after surgery. Strong or very strong compensatory sweating was observed in 17.5% of cases 3 months after ETS, in 14.1% after 12 months and in 23.6% after 36 months.

CONCLUSIONS

Thoracic sympathicotomy with clips is a safe treatment that provides satisfactory longterm results. The incidence of side-effects (intercostal pain, compensatory sweating) is high and does not change with time in most of the cases.

摘要

未标注

原发性多汗症胸交感神经切除术后的副作用包括疼痛和代偿性/反射性出汗。本研究的目的是评估夹闭式内镜胸交感神经切断术的效果,重点关注术后副作用的发生率。

材料与方法

283例患者接受了夹闭式T3 - T4胸交感神经切断术。所有病例均采用俯卧位双侧手术并进行二氧化碳气腹。采用视觉模拟评分法(VAS,0分表示无出汗;10分表示最大出汗量)评估疾病的主观严重程度,术后评估原发性部位出汗的复发情况、代偿性出汗和足底出汗的强度及动态变化。在术后3个月、12个月和36个月的门诊随访中获取随访数据。总体随访应答率为74.6%。

结果

无死亡病例。围手术期并发症包括6例气胸。双侧手术的平均时长为57分钟。所有患者(100%)术后均出现肋间疼痛,平均持续时间为21.88天,但72.6%的病例在术后48小时内无需任何药物治疗。内镜胸交感神经切断术(ETS)后3个月,17.5%的病例出现强烈或非常强烈的代偿性出汗;12个月后为14.1%;36个月后为23.6%。

结论

夹闭式胸交感神经切断术是一种安全的治疗方法,可提供令人满意的长期效果。副作用(肋间疼痛、代偿性出汗)的发生率较高,且在大多数情况下不随时间变化。

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