Clinical Trials Unit, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK.
Curr Opin Obstet Gynecol. 2013 Aug;25(4):320-6. doi: 10.1097/GCO.0b013e3283630e9c.
Long-term data from the studies of various endometrial ablation techniques are beginning to emerge. This review appraises the current literature on endometrial ablation for heavy menstrual bleeding, with particular emphasis on second-generation techniques, and their effectiveness, rates of repeat and further interventions and adverse events occurring 1 year or more after the procedure.
Second-generation, nonhysteroscopic techniques are marginally superior to hysteroscopic approaches, in terms of amenorrhoea, refractory menorrhagia and satisfaction rates. Hysterectomy rates are around 20% at 2 years, with a further 3-5% having repeat ablations. Bipolar radiofrequency and microwave ablation give rise to higher amenorrhoea rates than thermal balloon ablation, and are less likely to require repeat or further intervention.
Endometrial ablation is a well tolerated and effective procedure for the treatment of heavy menstrual bleeding. Second-generation techniques provide greater benefit than hysteroscopic techniques, with shorter procedural times and the possibility of outpatient treatment. Chronic pelvic pain frequently resolves after ablation, but can also develop de novo. Pregnancy outcomes are poor and continuing contraception is recommended.
各种子宫内膜消融技术的长期数据开始出现。本综述评估了子宫内膜消融治疗月经过多的当前文献,特别强调第二代技术及其有效性、再次干预和不良事件的发生率,这些事件发生在手术后 1 年或更长时间。
第二代非宫腔镜技术在闭经、难治性月经过多和满意度方面略优于宫腔镜方法。2 年内子宫切除术率约为 20%,另有 3-5%需要重复消融。双极射频和微波消融导致闭经的发生率高于热球消融,且不太可能需要重复或进一步干预。
子宫内膜消融术是一种耐受性好、治疗月经过多有效的方法。第二代技术比宫腔镜技术提供更大的益处,具有更短的手术时间和门诊治疗的可能性。消融后慢性盆腔疼痛通常会缓解,但也可能新出现。妊娠结局不佳,建议继续避孕。