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低至中级别涎腺导管癌伴腮腺破骨细胞样巨细胞瘤:一例具有独特病理特征的罕见病例。

Low to intermediate grade salivary duct carcinoma associated with osteoclast like-giant cell tumor of parotid gland: a rare case with distinct pathological features.

作者信息

Pasricha Sunil, Gandhi Jatin S, Mehta Anurag, Gupta Gurudutt, Pradhan Tapaswini

机构信息

Department of Histopathology, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, Delhi, India.

出版信息

J Cancer Res Ther. 2013 Apr-Jun;9(2):314-6. doi: 10.4103/0973-1482.113406.

Abstract

Osteoclast like-giant cell tumor of the salivary gland is an extremely rare tumor with distinct pathological features and unknown histogenesis. The neoplastic nature of these tumors in itself is questionable. We present the twentieth case in English literature of primary osteoclast like-giant cell tumor with accompanying low to intermediate grade salivary duct carcinoma of parotid gland, metastasizing to the ipsilateral cervical lymph node. As far as we know this is the second case with lymph node metastasis. Due to the rarity of the tumor its exact biological course is uncertain. We present and discuss this rare case with special emphasis on the histology, immunohistochemistry, and histogenesis.

摘要

唾液腺破骨细胞样巨细胞瘤是一种极为罕见的肿瘤,具有独特的病理特征且组织发生不明。这些肿瘤本身的肿瘤性质存在疑问。我们报告了英文文献中第20例原发性破骨细胞样巨细胞瘤,伴有腮腺低至中度分级的涎腺导管癌,并转移至同侧颈部淋巴结。据我们所知,这是第二例发生淋巴结转移的病例。由于该肿瘤罕见,其确切的生物学过程尚不确定。我们呈现并讨论这一罕见病例,特别强调其组织学、免疫组化和组织发生。

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