Salih Abdulwahid M, Abdulla Berwn A, Abdullah Ari M, Kakamad Fahmi H, Hassan Zana H, Ali Razhan K, Kakamad Suhaib H
College of Medicine, University of Sulaimani, Sulaimani, Iraq.
Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
Ann Med Surg (Lond). 2022 Mar 28;77:103509. doi: 10.1016/j.amsu.2022.103509. eCollection 2022 May.
The osteoclast-like giant cell is a benign tumor that presents as either an isolated benign tumor or one with a carcinomatous component. This study aims to report a rare case of osteoclast-like giant cell tumor (GCT) of the parotid gland.
A 67-year-old female presented with a painless left pre-auricular swelling of 2-month duration which increased in size gradually over that period. On examination, there was a firm, mobile mass with well-defined borders in the left parotid gland. Fine needle aspiration cytology showed a giant cell-rich lesion that was highly cellular and contained a large number of osteoclast-like multinucleated giant cells, with clusters of spindle and epithelioid cells. Total parotidectomy was performed. After the operation, the patient was sent for radiotherapy.
The histogenesis and exact nature of this tumor are unknown although numerous ideas have been put forward. The most common clinical manifestation is a painless slow-growing tumor in the parotid area. Primary osteoclast-like GCT of the salivary gland might show concomitant benign or malignant neoplasms. There is also a "pure form" of the tumor that has no accompanying neoplasm.
GCT of the parotid gland is a rare tumor. The histogenesis and nature of parotid gland GCT are not completely understood. The treatment of choice is total excision followed by radiotherapy.
破骨细胞样巨细胞瘤是一种良性肿瘤，可表现为孤立的良性肿瘤或伴有癌性成分的肿瘤。本研究旨在报告一例罕见的腮腺破骨细胞样巨细胞瘤（GCT）病例。
一名67岁女性，左侧耳前出现无痛性肿胀2个月，在此期间逐渐增大。检查发现左侧腮腺有一个边界清晰、质地坚硬、可活动的肿块。细针穿刺细胞学检查显示为富含巨细胞的病变，细胞高度密集，包含大量破骨细胞样多核巨细胞，以及梭形细胞和上皮样细胞簇。进行了腮腺全切术。术后患者接受了放疗。
尽管已经提出了许多观点，但该肿瘤的组织发生和确切性质尚不清楚。最常见的临床表现是腮腺区无痛性生长缓慢的肿瘤。涎腺原发性破骨细胞样GCT可能伴有良性或恶性肿瘤。也有一种“纯形式”的肿瘤，不伴有其他肿瘤。
腮腺GCT是一种罕见肿瘤。腮腺GCT的组织发生和性质尚未完全明确。首选治疗方法是全切术，术后进行放疗。
