Yoshida M
Department of Surgery, School of Medicine, University of Niigata, Japan.
Nihon Geka Gakkai Zasshi. 1990 Apr;91(4):451-63.
Using 5 conscious mongrel dogs, a study was conducted to investigate the vagotomy on gastroduodenal movements. At the first operation, the electrodes and strangage force transducers were attached to the antrum and duodenum; after making an electromyogram and recording contraction waves simultaneously, a transthoracic truncal vagotomy (TV) was performed and similar recordings were done. In order to evaluate the effect of TV on antral motility as well as antroduodenal coordination, the motility of the antrum and average contraction force per time unit were measured before and after TV. Furthermore induced inhibition and propagated excitation were analyzed referring to lag cross correlations before and after TV. The results were as follows: As compared with pre-vagotomy values, the post-vagotomy measured amount of motility as well as the average contraction force were reduced. Before TV in digestive state both propagated excitation and induced inhibition could be recognized. During phase II in digestive state only propagated excitation could be demonstrated, while in phase III both were absent. After TV in digestive state propagated excitation was noted, but the propagating time was shorter than before TV. Induced inhibition could not be demonstrated any longer. Furthermore, during phases II and III in the interdigestive state both were not noted.
使用5只清醒的杂种狗，进行了一项研究以调查迷走神经切断术对胃十二指肠运动的影响。在第一次手术中，将电极和应变力传感器连接到胃窦和十二指肠；在同时进行肌电图和记录收缩波后，进行经胸迷走神经干切断术（TV）并进行类似记录。为了评估TV对胃窦运动以及胃窦十二指肠协调性的影响，在TV前后测量胃窦的运动性和每单位时间的平均收缩力。此外，参照TV前后的滞后互相关分析诱发性抑制和传播性兴奋。结果如下：与迷走神经切断术前的值相比，迷走神经切断术后测量的运动性以及平均收缩力均降低。在消化状态下TV前，传播性兴奋和诱发性抑制均可被识别。在消化状态的II期，仅能证明传播性兴奋，而在III期两者均不存在。在消化状态下TV后，注意到传播性兴奋，但传播时间比TV前短。诱发性抑制不再能被证明。此外，在消化间期的II期和III期均未观察到两者。
