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伴胸腺瘤的副肿瘤性脑炎:一例报告

Paraneoplastic encephalitis associated with thymoma: a case report.

作者信息

Suh Jee Won, Haam Seok Jin, Song Suk Won, Shin Yu Rim, Paik Hyo Chae, Lee Doo Yun

机构信息

Department of Thoracic and Cardiovascular Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Korea.

出版信息

Korean J Thorac Cardiovasc Surg. 2013 Jun;46(3):234-6. doi: 10.5090/kjtcs.2013.46.3.234. Epub 2013 Jun 5.

DOI:10.5090/kjtcs.2013.46.3.234
PMID:23772416
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3680614/
Abstract

A 42-year-old woman with short-term memory loss visited Gangnam Severance Hospital, and her chest X-ray and computed tomography revealed a right anterior mediastinal mass. On hospital day two, she suddenly presented personality changes and a drowsy mental status, so she required ventilator care in the intensive care unit. She underwent thymectomy, and was pathologically diagnosed with thymoma, type B1. Her mental status eventually recovered by postoperative day 90. Paraneoplastic encephalopathy associated with thymoma is very rare, and symptoms can be improved by thymectomy. We report a case of paraneoplastic encephalopathy associated with a thymoma.

摘要

一名患有短期记忆丧失的42岁女性前往江南Severance医院就诊,其胸部X光和计算机断层扫描显示右前纵隔有一个肿块。在住院第二天,她突然出现人格改变和嗜睡的精神状态,因此需要在重症监护病房接受呼吸机护理。她接受了胸腺切除术,病理诊断为B1型胸腺瘤。她的精神状态最终在术后第90天恢复。与胸腺瘤相关的副肿瘤性脑病非常罕见,胸腺切除术可改善症状。我们报告一例与胸腺瘤相关的副肿瘤性脑病病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e8/3680614/a786a4b85900/kjtcs-46-234-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e8/3680614/fd249cfc7bcd/kjtcs-46-234-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e8/3680614/a786a4b85900/kjtcs-46-234-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e8/3680614/fd249cfc7bcd/kjtcs-46-234-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18e8/3680614/a786a4b85900/kjtcs-46-234-g002.jpg

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本文引用的文献

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Interact Cardiovasc Thorac Surg. 2009 Oct;9(4):755-6. doi: 10.1510/icvts.2009.211276. Epub 2009 Jul 21.
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Paraneoplastic limbic encephalitis attributable to thymoma.胸腺瘤所致副肿瘤性边缘叶脑炎
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Clinical, magnetic resonance imaging, and electroencephalographic findings in paraneoplastic limbic encephalitis.副肿瘤性边缘叶脑炎的临床、磁共振成像及脑电图检查结果
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