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纵隔肿物:切还是不切?

Mediastinal mass: to resect or not to resect?

作者信息

Simons Anneliese, Finnerty James, Wilson Martin

机构信息

Department of Respiratory Medicine, Countess of Chester Hospital, Chester, UK.

Department of Neurology, Countess of Chester Hospital, Chester, UK.

出版信息

BMJ Case Rep. 2015 Apr 21;2015:bcr2015209962. doi: 10.1136/bcr-2015-209962.

DOI:10.1136/bcr-2015-209962
PMID:25899515
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4420806/
Abstract

We describe a case of a 63-year-old man presenting in an acute confusional state with a markedly abnormal chest radiograph. During investigation, he developed aspiration pneumonia and was ventilated on the intensive care unit before confirming that he had autoimmune encephalopathy secondary to benign thymoma. After treatment with intravenous immunoglobulins he made an impressive recovery allowing him to be transferred to a tertiary unit for resection of the underlying mass, thus resulting in an excellent neurological recovery.

摘要

我们描述了一例63岁男性患者,其以急性意识模糊状态就诊,胸部X线片明显异常。在检查过程中,他发生了吸入性肺炎,并在重症监护病房接受机械通气,之后确诊为继发于良性胸腺瘤的自身免疫性脑病。经静脉注射免疫球蛋白治疗后,他恢复显著,得以转至三级医疗单位切除潜在肿块,从而实现了极佳的神经功能恢复。

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1
Mediastinal mass: to resect or not to resect?纵隔肿物:切还是不切?
BMJ Case Rep. 2015 Apr 21;2015:bcr2015209962. doi: 10.1136/bcr-2015-209962.
2
Computer tomography of the anterior mediastinum in patients with myasthenia gravis and suspected thymoma.
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[Thymoma with Hemorrhage and Necrosis Presenting with Fever and Chest Pain;Report of a Case].[伴有出血和坏死的胸腺瘤伴发热和胸痛;病例报告]
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本文引用的文献

1
Paraneoplastic encephalitis associated with thymoma: a case report.伴胸腺瘤的副肿瘤性脑炎:一例报告
Korean J Thorac Cardiovasc Surg. 2013 Jun;46(3):234-6. doi: 10.5090/kjtcs.2013.46.3.234. Epub 2013 Jun 5.
2
Clinical relevance of positive voltage-gated potassium channel (VGKC)-complex antibodies: experience from a tertiary referral centre.电压门控钾通道复合物(VGKC)抗体阳性的临床意义:来自一个三级转诊中心的经验。
J Neurol Neurosurg Psychiatry. 2014 Jun;85(6):625-30. doi: 10.1136/jnnp-2013-305218. Epub 2013 Jun 11.
3
Thymoma-associated progressive encephalomyelitis with rigidity and myoclonus successfully treated with thymectomy and intravenous immunoglobulin.胸腺切除联合静脉注射免疫球蛋白成功治疗与胸腺瘤相关的进行性脑脊髓炎伴强直和肌阵挛
Eur Neurol. 2011;66(6):328-30. doi: 10.1159/000332033. Epub 2011 Nov 11.
4
[Anti-VGKC antibody-associated limbic encephalitis/Morvan syndrome].[抗电压门控性钾通道抗体相关边缘叶脑炎/莫旺综合征]
Brain Nerve. 2010 Apr;62(4):339-45.
5
Paraneoplastic extra limbic encephalitis associated with thymoma.与胸腺瘤相关的副肿瘤性边缘叶外脑炎。
Interact Cardiovasc Thorac Surg. 2009 Oct;9(4):755-6. doi: 10.1510/icvts.2009.211276. Epub 2009 Jul 21.
6
Autoantibody profiles and neurological correlations of thymoma.胸腺瘤的自身抗体谱及其与神经系统的相关性。
Clin Cancer Res. 2004 Nov 1;10(21):7270-5. doi: 10.1158/1078-0432.CCR-04-0735.