Bezgin T, Yilmaz A D, Celik B N, Sönmez H
Department of Pedodontics, Faculty of Dentistry, Ankara University, Ankara, Turkey.
Int Endod J. 2014 Jan;47(1):41-9. doi: 10.1111/iej.12144. Epub 2013 Jun 17.
To present two case reports describing the treatment of immature teeth with necrotic pulps using concentrated platelet-rich plasma (cPRP) with 12-month clinical and radiographic follow-up.
Root canal revascularization was performed on immature permanent teeth clinically and radiographically diagnosed as requiring root canal treatment. Following disinfection of the canal space with triple antibiotic paste (1 : 1 : 1: ciprofloxacin, metronidazole and cefaclor), a tissue scaffold was created with cPRP prepared using 2-step centrifugation. The final restoration was completed with white mineral trioxide aggregate and composite resin. The patients were recalled for clinical and radiographic evaluations every 3 months. At the 12-month follow-up apical closure by narrowing of the apical foramen and convergence of the apical walls in the treated teeth was observed.
呈现两例病例报告，描述使用浓缩富血小板血浆（cPRP）治疗牙髓坏死的未成熟恒牙，并进行为期12个月的临床和影像学随访。
对临床和影像学诊断为需要根管治疗的未成熟恒牙进行根管再血管化治疗。用三联抗生素糊剂（1:1:1：环丙沙星、甲硝唑和头孢克洛）对根管空间进行消毒后，使用两步离心法制备的cPRP构建组织支架。最后用白色矿物三氧化物凝聚体和复合树脂完成修复。每3个月召回患者进行临床和影像学评估。在12个月的随访中，观察到治疗牙齿的根尖孔变窄和根尖壁收敛导致根尖闭合。
