Ghilardi G, Pecis C, Bortolani E M, De Bitonto A
Istituto di Chirurgia Generale e Cardiovascolare, Università di Milano.
Minerva Med. 1990 May;81(5):427-31.
The case of a 24 year old man affected with Wiskott-Aldrich syndrome (WAS) is reported. The review of the charts of previous hospital admissions revealed the presence of an inherited trait and a long history of recurrent infections and hemorrhages. This young man was referred to our surgical department with the diagnosis of right lower limb gangrene, but the biopsy showed the lesion being due to cutaneous malignant lymphoma characterized by large polymorphic cells. All clinical and immunological elements typical of WAS were present: they are discussed with regard to the recent literature.
报告了一例患有威斯科特-奥尔德里奇综合征（WAS）的24岁男性病例。回顾其既往住院病历发现存在一种遗传特征以及反复感染和出血的长期病史。该青年男子因右下肢坏疽诊断被转诊至我们外科，但活检显示病变是由具有大的多形性细胞特征的皮肤恶性淋巴瘤引起。WAS所有典型的临床和免疫学特征均存在：结合近期文献对这些特征进行了讨论。
