Suzuki T, Yoshida Y, Kikuchi K, Kyuno K, Tanji H, Saito I, Kusumoto S
Dept. of Pathology, Kushiro Red Cross Hospital.
Gan No Rinsho. 1988 Sep;34(11):1595-602.
An 80-year-old man, complaining of multiple fungating growth on his right leg, was hospitalized. A review of his previous history revealed that he had undergone three operations because of repeating osteomyelitis. A clinical examination showed that a tumor was localized on the right leg. Light microscopy revealed that tumor was composed of diffuse large round cell proliferations. Malignant lymphoma was suspected, but was difficult to distinguish in the undifferentiated carcinoma. Electron microscopically, extensive cytoplasmic processes resembling microvilli from the circumferential surface membrane were observed, but desmosomes, tonofilaments, secretory products or basal lamina were not seen. Immunohistochemically, IgG was demonstrated on the tumor cells. These findings led us to diagnoses an anemone cell tumor, originating from a malignant lymphoma and arising from osteomyelitis.
一名80岁男性因右腿出现多处蕈状肿物而入院。回顾其既往史发现，他曾因反复发生骨髓炎接受过三次手术。临床检查显示肿瘤位于右腿。光镜检查显示肿瘤由弥漫性大圆形细胞增殖构成。怀疑为恶性淋巴瘤，但在未分化癌中难以鉴别。电镜下观察到肿瘤细胞外周表面膜有大量类似微绒毛的胞质突起，但未见桥粒、张力丝、分泌产物或基膜。免疫组化显示肿瘤细胞上有IgG。这些发现使我们诊断为海葵细胞瘤，起源于恶性淋巴瘤且由骨髓炎引起。
