Centro de Estudios Ultrasonograficos Perinatales, Valencia, Venezuela.
Fetal Diagn Ther. 2013;34(2):85-9. doi: 10.1159/000351657. Epub 2013 Jun 17.
The aims of this study were to determine (a) whether the normal pericallosal vascular map can be visualized using color Doppler ultrasonography in normal fetuses in the first trimester of pregnancy and (b) whether an abnormal pericallosal artery (PA) vascular map can be observed in fetuses with corpus callosum agenesis early in pregnancy.
In 150 consecutive women undergoing a routine ultrasound examination at 11-14 weeks of gestation in our high-risk pregnancy unit as part of screening for chromosomal abnormalities, a mid-sagittal view of the fetal head was obtained to measure nuchal translucency thickness, assess nasal bones in their corresponding two oblique planes and intracranial translucency. In this view and with color Doppler ultrasonography, we evaluated the vascular map of the PA.
The vascular map of the PA was observed in 97.02% of cases at the 11- to 14-week evaluation (144/150 fetuses). Two cases with an abnormal PA were identified and confirmed as corpus callosum agenesis in the second trimester, 1 due to trisomy 13 and the other due to triploidy.
The PA can routinely be observed at the first-trimester evaluation with color Doppler ultrasonography using the mid-sagittal view of the fetal head. The presence of an abnormal vascular map of the PA by Doppler ultrasonography at 11-14 weeks raises the suspicion of corpus callosum agenesis.
本研究旨在确定：(a) 正常胼胝体血管图谱是否可通过彩色多普勒超声在妊娠 11-14 周的正常胎儿中显示；(b) 在妊娠早期胼胝体发育不全的胎儿中是否可以观察到异常的胼胝体动脉（PA）血管图谱。
在我们的高危妊娠科，150 例连续进行常规超声检查的孕妇在妊娠 11-14 周进行，作为染色体异常筛查的一部分，获得胎儿头部的正中矢状切面以测量颈项透明层厚度，评估鼻骨在其相应的两个斜平面上和颅内透明层。在该切面和彩色多普勒超声下，我们评估了 PA 的血管图谱。
在 11-14 周评估中，97.02%的病例观察到了 PA 的血管图谱（144/150 例胎儿）。发现并确认了 2 例 PA 异常，在妊娠中期发现为胼胝体发育不全，1 例是由于三体 13，另 1 例是由于三倍体。
通过彩色多普勒超声使用胎儿头部正中矢状切面可以在妊娠 11-14 周常规观察 PA。在 11-14 周通过多普勒超声观察到 PA 的异常血管图谱提示胼胝体发育不全。
