From the Department of Fetal Medicine (B.D.K.), Universitaire Ziekenhuizen Leuven, Leuven, Belgium.
Department of Obstetrics and Gynaecology (B.D.K.), AZ Groeninge, Kortrijk, Belgium.
AJNR Am J Neuroradiol. 2018 Mar;39(3):589-596. doi: 10.3174/ajnr.A5562. Epub 2018 Feb 22.
Anomalies of the corpus callosum are rare. Routine scanning in midtrimester of the pregnancy often fails to identify defective development. The purpose of the study was to identify the pericallosal artery and all its main branching arteries during early gestation from the first trimester onward, to measure the length of the pericallosal artery during its development, and to establish a normal vascular map for each week of development.
We performed a single-center prospective, longitudinal clinical study in 15 patients between 11 and 22 weeks of gestation. The origin and course of the different blood vessels were identified.
There was a linear association among gestational age, the biparietal diameter, and the length of the pericallosal artery. The curvature of the developing pericallosal artery increases linearly with the gestational age and biparietal diameter, and 4 variations of branching of the callosomarginal artery were observed.
The pericallosal artery and its branches can be identified and measured from 11 weeks on, and the pericallosal artery takes its characteristic course. A defective course or an abnormal biometry of the pericallosal artery could be an early sonographic marker of abnormal development of the corpus callosum.
胼胝体异常较为罕见。妊娠中期的常规扫描往往无法识别发育缺陷。本研究的目的是在妊娠早期（即从第一孕期开始）识别胼胝体周围动脉及其所有主要分支动脉，测量胼胝体动脉在发育过程中的长度，并为每个发育周建立正常的血管图谱。
我们在 15 名妊娠 11 至 22 周的患者中进行了一项单中心前瞻性纵向临床研究。确定了不同血管的起源和走行。
在胎龄、双顶径和胼胝体动脉长度之间存在线性关联。发育中的胼胝体动脉的曲率随胎龄和双顶径呈线性增加，并且观察到胼胝体缘动脉的 4 种分支变异。
从 11 周开始即可识别和测量胼胝体动脉及其分支，并且胼胝体动脉具有其特征性走行。胼胝体动脉的异常走行或异常生物测量可能是胼胝体发育异常的早期超声标志物。
