Tóth Veronika, Somlai Beáta, Hársing Judit, Hatvani Zsófia, Kárpáti Sarolta
Semmelweis Egyetem, Általános Orvostudományi Kar, Bőr-, Nemikórtani és Bőronkológiai Klinika, Budapest.
Orv Hetil. 2013 Jun 23;154(25):969-76. doi: 10.1556/OH.2013.29629.
Survival of patients with malignant melanoma primarily depends on tumor stage. Hungarian National Cancer Registry does not specify tumors according to TNM stages.
The authors aimed to survey the stage distribution of melanomas at the Department of Dermatology, Dermatooncology and Venerology, Semmelweis University.
1160 patients (558 males and 602 females, aged 60.5±16 and 57±17 years, respectively) diagnosed with cutaneous melanoma between 2004-2009 were included.
In comparison with international studies, the case distribution was favorable in stages IA and IV, i.e. the proportion of early melanomas was relatively high (IA: 43.8%), while the incidence in stage IV was low (0.4%). In stages IB-IIA the incidence was significantly lower, while in IIC, IIIA, IIIB it was higher as compared to published data from Western-Europe, Australia and the United States.
The study underlines the necessity of prevention and awareness campaigns that may result in increase of early diagnosis of melanomas.
恶性黑色素瘤患者的生存率主要取决于肿瘤分期。匈牙利国家癌症登记处并未根据TNM分期对肿瘤进行分类。
作者旨在调查塞梅尔维斯大学皮肤科、皮肤肿瘤学与性病学系黑色素瘤的分期分布情况。
纳入了2004年至2009年间诊断为皮肤黑色素瘤的1160例患者(男性558例,女性602例,年龄分别为60.5±16岁和57±17岁)。
与国际研究相比,IA期和IV期的病例分布情况较好,即早期黑色素瘤的比例相对较高(IA期:43.8%),而IV期的发病率较低(0.4%)。与西欧、澳大利亚和美国公布的数据相比,IB-IIA期的发病率显著较低,而IIC期、IIIA期、IIIB期的发病率较高。
该研究强调了开展预防和提高 awareness 活动的必要性,这些活动可能会提高黑色素瘤的早期诊断率。 (注:原文中awareness未翻译完整,推测可能是“提高意识”之类的意思,但按要求未补充完整)